GO:0006429:   leucyl-tRNA aminoacylation
The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2"-OH group of a leucine-accetping tRNA. The 2"-O-aminoacyl-tRNA will ultimately migrate to the 3" position via transesterification.