ENSDARG00000019144


Danio rerio

Features
Gene ID: ENSDARG00000019144
  
Biological name :rab4a
  
Synonyms : Q6PHI9 / rab4a / RAB4a, member RAS oncogene family
  
Possible biological names infered from orthology : P20338 / P56371 / Ras-related protein Rab-4A
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 24295896
Gene end: 24311628
  
Corresponding Affymetrix probe sets: Dr.15376.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000012097
NCBI entrez gene - 403031     See in Manteia.
RefSeq - NM_001126381
RefSeq Peptide - NP_001119853
swissprot - B0V0U3
swissprot - Q6PHI9
ZFIN ID - ZDB-GENE-040525-1
Ensembl - ENSDARG00000019144
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB4AENSGALG00000036218Gallus gallus
 RAB4AENSG00000168118Homo sapiens
 Rab4aENSMUSG00000019478Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rab4b / RAB4B, member RAS oncogene family / Q91ZR1* / P61018* / RAB4B-EGLN2* / RAB4B-EGLN2 readthrough (NMD candidate)*ENSDARG0000001217787
rab14 / RAB14, member RAS oncogene family / P61106* / Q91V41*ENSDARG0000007424659
rab14l / RAB14, member RAS oncogene family, likeENSDARG0000003518858
rab2a / RAB2A, member RAS oncogene family / P53994* / P61019* / Ras-related protein Rab-2A *ENSDARG0000002026152
rab11bb / RAB11B, member RAS oncogene family, b / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*ENSDARG0000009008644
rab11ba / RAB11B, member RAS oncogene family, a / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*ENSDARG0000004187844
rab11al / RAB11a, member RAS oncogene family, likeENSDARG0000001434043
rab11a / RAB11a, member RAS oncogene familyENSDARG0000004145043
rab25a / RAB25, member RAS oncogene family a / RAB25* / Q9WTL2* / P57735* / RAB25, member RAS oncogene family*ENSDARG0000005880042
rab25b / RAB25, member RAS oncogene family b / RAB25* / P57735* / RAB25, member RAS oncogene family*ENSDARG0000005295440
rab39bb / RAB39B, member RAS oncogene family b / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*ENSDARG0000003650138
rab39ba / RAB39B, member RAS oncogene family a / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*ENSDARG0000001931238
Q6DHC1 / rab18b / RAB18B, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*ENSDARG0000009834437
rab18a / RAB18A, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*ENSDARG0000005529136
rab42b / RAB42, member RAS oncogene familyENSDARG0000010117035
rab42a / RAB42, member RAS oncogene family aENSDARG0000003421535
si:dkey-34d22.2ENSDARG0000010037933
si:dkey-34d22.5ENSDARG0000010486528
CU571310.1 / RAB42* / Q8N4Z0* / RAB42, member RAS oncogene family*ENSDARG0000010258028
si:ch211-247i17.1ENSDARG0000007672719


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030100 regulation of endocytosis IBA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032593 insulin-responsive compartment IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs
RAB geranylgeranylation
MET receptor recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
Show

 ZFA:0005249 vasculature vasculature malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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