ENSDARG00000076010


Danio rerio

Features
Gene ID: ENSDARG00000076010
  
Biological name :twist1b
  
Synonyms : twist1b / twist family bHLH transcription factor 1b
  
Possible biological names infered from orthology : P26687 / Q15672 / Q8WVJ9 / TWIST1 / TWIST2 / twist basic helix-loop-helix transcription factor 1 / twist basic helix-loop-helix transcription factor 2 / twist family bHLH transcription factor 1 / twist family bHLH transcription factor 2
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 19732543
Gene end: 19734149
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000052926
Ensembl peptide - ENSDARP00000124909
NCBI entrez gene - 550518     See in Manteia.
RefSeq - NM_001017820
RefSeq Peptide - NP_001017820
swissprot - F8W609
swissprot - Q568M7
ZFIN ID - ZDB-GENE-050417-357
Ensembl - ENSDARG00000076010
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TWIST2ENSGALG00000004274Gallus gallus
 Q15672ENSG00000122691Homo sapiens
 Q8WVJ9ENSG00000233608Homo sapiens
 P26687ENSMUSG00000035799Mus musculus
 Twist2ENSMUSG00000007805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
twist1a / twist family bHLH transcription factor 1a / Q8WVJ9* / TWIST1* / TWIST2* / P26687* / Q15672* / twist family bHLH transcription factor 1* / twist family bHLH transcription factor 2*...ENSDARG0000003040282
twist2 / Q15672* / Q8WVJ9* / TWIST1* / P26687* / twist family bHLH transcription factor 2* / twist family bHLH transcription factor 1* / twist basic helix-loop-helix transcription factor 1*...ENSDARG0000007826674
twist3ENSDARG0000001964663
tcf15 / transcription factor 15ENSDARG0000006754429
scxb / scleraxis bHLH transcription factor b / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000001163528
scxa / scleraxis bHLH transcription factor a / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000003569528
tal1 / O93507 / T-cell acute lymphocytic leukemia 1 / P22091* / P17542* / TAL bHLH transcription factor 1, erythroid differentiation factor*ENSDARG0000001993028
si:ch211-246m6.4ENSDARG0000004285726
hand2 / heart and neural crest derivatives expressed 2 / P61296* / Q61039* / Heart- and neural crest derivatives-expressed protein 2 *ENSDARG0000000830525
CABZ01066694.1 / LYL1* / P12980* / P27792* / Protein lyl-1 * / LYL1, basic helix-loop-helix family member*ENSDARG0000011017824
tal2 / T-cell acute lymphocytic leukemia 2 / Q16559* / Q62282* / TAL bHLH transcription factor 2*ENSDARG0000004204121
nhlh2 / nescient helix loop helix 2 / NHLH1* / Q02575* / Q64221* / Q02576* / Q02577* / nescient helix-loop-helix 1*ENSDARG0000002549521


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR015789  Twist-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IGI
 biological_processGO:0009953 dorsal/ventral pattern formation IGI
 biological_processGO:0030500 regulation of bone mineralization IMP
 biological_processGO:0060037 pharyngeal system development IGI
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye absent , abnormal
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 ZFA:0000109 forebrain forebrain anterior region non-functional , abnormal
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 ZFA:0000135 notochord notochord absent , abnormal
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 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
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 ZFA:0001216 splanchnocranium splanchnocranium hypoplastic , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton hypoplastic , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel sprouting angiogenesis decreased occurrence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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