ENSG00000021776


Homo sapiens

Features
Gene ID: ENSG00000021776
  
Biological name :AQR
  
Synonyms : AQR / aquarius intron-binding spliceosomal factor / O60306
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q14
Gene start: 34851782
Gene end: 34969839
  
Corresponding Affymetrix probe sets: 212583_at (Human Genome U133 Plus 2.0 Array)   212584_at (Human Genome U133 Plus 2.0 Array)   228694_at (Human Genome U133 Plus 2.0 Array)   239895_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445700
Ensembl peptide - ENSP00000453278
Ensembl peptide - ENSP00000156471
NCBI entrez gene - 9716     See in Manteia.
OMIM - 610548
RefSeq - NM_014691
RefSeq Peptide - NP_055506
swissprot - A0A024R9L1
swissprot - H0YH15
swissprot - H0YLN9
swissprot - O60306
Ensembl - ENSG00000021776
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aqrENSDARG00000016775Danio rerio
 AQRENSGALG00000009838Gallus gallus
 AqrENSMUSG00000040383Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZNFX1 / Q9P2E3 / zinc finger NFX1-type containing 1ENSG0000012420118
SETX / Q7Z333 / senataxinENSG0000010729015


Protein motifs (from Interpro)
Interpro ID Name
 IPR026300  CWF11 family
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032174  Intron-binding protein aquarius, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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