ENSG00000065150


Homo sapiens

Features
Gene ID: ENSG00000065150
  
Biological name :IPO5
  
Synonyms : importin 5 / IPO5 / O00410
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q32.2
Gene start: 97953658
Gene end: 98024297
  
Corresponding Affymetrix probe sets: 211952_at (Human Genome U133 Plus 2.0 Array)   211953_s_at (Human Genome U133 Plus 2.0 Array)   211954_s_at (Human Genome U133 Plus 2.0 Array)   211955_at (Human Genome U133 Plus 2.0 Array)   236906_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417647
Ensembl peptide - ENSP00000417162
Ensembl peptide - ENSP00000417721
Ensembl peptide - ENSP00000487097
Ensembl peptide - ENSP00000420491
Ensembl peptide - ENSP00000420284
Ensembl peptide - ENSP00000420149
Ensembl peptide - ENSP00000420079
Ensembl peptide - ENSP00000420043
Ensembl peptide - ENSP00000419860
Ensembl peptide - ENSP00000419797
Ensembl peptide - ENSP00000419766
Ensembl peptide - ENSP00000419764
Ensembl peptide - ENSP00000419398
Ensembl peptide - ENSP00000419166
Ensembl peptide - ENSP00000419003
Ensembl peptide - ENSP00000418393
Ensembl peptide - ENSP00000417993
Ensembl peptide - ENSP00000261574
Ensembl peptide - ENSP00000350219
Ensembl peptide - ENSP00000385938
Ensembl peptide - ENSP00000408885
NCBI entrez gene - 3843     See in Manteia.
OMIM - 602008
RefSeq - XM_017020562
RefSeq - NM_002271
RefSeq - XM_005254052
RefSeq - XM_005254053
RefSeq - XM_011521087
RefSeq - XM_011521088
RefSeq - XM_011521089
RefSeq - XM_011521090
RefSeq Peptide - NP_002262
swissprot - C9JZD8
swissprot - C9JZ53
swissprot - C9JXE0
swissprot - C9JQT6
swissprot - C9JMV5
swissprot - C9J875
swissprot - C9J583
swissprot - F8WF30
swissprot - H0Y3V4
swissprot - H0Y8C6
swissprot - A0A024RDY0
swissprot - O00410
swissprot - E7EX05
swissprot - E7EWK4
swissprot - E7EV12
swissprot - E7ETV8
swissprot - E7ETV3
swissprot - E7ESZ1
swissprot - E7EQT5
swissprot - E7ESA1
Ensembl - ENSG00000065150
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpnb3ENSDARG00000040245Danio rerio
 ENSGALG00000031299Gallus gallus
 ENSGALG00000032430Gallus gallus
 Ipo5ENSMUSG00000030662Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60518 / RANBP6 / RAN binding protein 6ENSG0000013704078


Protein motifs (from Interpro)
Interpro ID Name
 IPR000357  HEAT repeat
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR034085  TOG domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IBA
 biological_processGO:0006607 NLS-bearing protein import into nucleus TAS
 biological_processGO:0006610 ribosomal protein import into nucleus IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0042307 positive regulation of protein import into nucleus ISS
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity TAS
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005643 nuclear pore TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031965 nuclear membrane IBA
 cellular_componentGO:0034399 nuclear periphery IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005095 GTPase inhibitor activity TAS
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IBA


Pathways (from Reactome)
Pathway description
vRNP Assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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