ENSG00000077235


Homo sapiens

Features
Gene ID: ENSG00000077235
  
Biological name :GTF3C1
  
Synonyms : general transcription factor IIIC subunit 1 / GTF3C1 / Q12789
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.1
Gene start: 27459555
Gene end: 27549913
  
Corresponding Affymetrix probe sets: 202320_at (Human Genome U133 Plus 2.0 Array)   35671_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000459231
Ensembl peptide - ENSP00000457449
Ensembl peptide - ENSP00000457476
Ensembl peptide - ENSP00000348510
Ensembl peptide - ENSP00000455417
Ensembl peptide - ENSP00000456187
NCBI entrez gene - 2975     See in Manteia.
OMIM - 603246
RefSeq - XM_017023188
RefSeq - NM_001286242
RefSeq - NM_001520
RefSeq Peptide - NP_001273171
RefSeq Peptide - NP_001511
swissprot - H3BRD0
swissprot - I3L1Z3
swissprot - H3BU55
swissprot - H3BU37
swissprot - Q12789
Ensembl - ENSG00000077235
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01083166.1ENSDARG00000099619Danio rerio
 GTF3C1ENSGALG00000007387Gallus gallus
 Gtf3c1ENSMUSG00000032777Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007309  B-block binding subunit of TFIIIC
 IPR035625  Tfc3, extended winged-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IC
 biological_processGO:0006359 regulation of transcription by RNA polymerase III IEA
 biological_processGO:0006383 transcription by RNA polymerase III IC
 biological_processGO:0006384 transcription initiation from RNA polymerase III promoter IBA
 biological_processGO:0009303 rRNA transcription TAS
 biological_processGO:0009304 tRNA transcription TAS
 biological_processGO:0042791 5S class rRNA transcription by RNA polymerase III IC
 biological_processGO:0042797 tRNA transcription by RNA polymerase III IC
 cellular_componentGO:0000127 transcription factor TFIIIC complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0000995 RNA polymerase III general transcription initiation factor activity IBA
 molecular_functionGO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001007 obsolete transcription factor activity, RNA polymerase III transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IC
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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