ENSG00000091039


Homo sapiens

Features
Gene ID: ENSG00000091039
  
Biological name :OSBPL8
  
Synonyms : OSBPL8 / oxysterol binding protein like 8 / Q9BZF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q21.2
Gene start: 76351797
Gene end: 76559809
  
Corresponding Affymetrix probe sets: 212582_at (Human Genome U133 Plus 2.0 Array)   212585_at (Human Genome U133 Plus 2.0 Array)   228986_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450238
Ensembl peptide - ENSP00000449919
Ensembl peptide - ENSP00000478240
Ensembl peptide - ENSP00000261183
Ensembl peptide - ENSP00000376939
Ensembl peptide - ENSP00000376940
Ensembl peptide - ENSP00000446886
Ensembl peptide - ENSP00000447235
Ensembl peptide - ENSP00000447483
Ensembl peptide - ENSP00000447744
Ensembl peptide - ENSP00000447893
Ensembl peptide - ENSP00000448394
Ensembl peptide - ENSP00000449618
NCBI entrez gene - 114882     See in Manteia.
OMIM - 606736
RefSeq - XM_017018769
RefSeq - NM_001003712
RefSeq - NM_001319652
RefSeq - NM_001319653
RefSeq - NM_001319655
RefSeq - NM_020841
RefSeq - XM_005268621
RefSeq - XM_006719224
RefSeq - XM_011537855
RefSeq - XM_011537856
RefSeq - XM_011537857
RefSeq - XM_017018768
RefSeq Peptide - NP_065892
RefSeq Peptide - NP_001003712
RefSeq Peptide - NP_001306581
RefSeq Peptide - NP_001306582
RefSeq Peptide - NP_001306584
swissprot - F8VQX7
swissprot - F8VS33
swissprot - F8VUA7
swissprot - F8VVD3
swissprot - F8VVE7
swissprot - F8VZ43
swissprot - F8VZB8
swissprot - Q9BZF1
swissprot - A0A024RBB8
swissprot - F8W060
swissprot - F8W1F1
Ensembl - ENSG00000091039
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OSBPL8ENSDARG00000039724Danio rerio
 OSBPL8ENSGALG00000010246Gallus gallus
 B9EJ86ENSMUSG00000020189Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSBPL5 / Q9H0X9 / oxysterol binding protein like 5ENSG0000002176254
Q9BXB5 / OSBPL10 / oxysterol binding protein like 10ENSG0000014464522
Q9BXB4 / OSBPL11 / oxysterol binding protein like 11ENSG0000014490921
OSBPL9 / Q96SU4 / oxysterol binding protein like 9ENSG0000011785920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0010891 negative regulation of sequestering of triglyceride IDA
 biological_processGO:0015914 phospholipid transport IDA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032148 activation of protein kinase B activity ISS
 biological_processGO:0036150 phosphatidylserine acyl-chain remodeling TAS
 biological_processGO:0045444 fat cell differentiation IDA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISS
 biological_processGO:0090204 protein localization to nuclear pore IEA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005548 phospholipid transporter activity TAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PS


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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