ENSG00000096063


Homo sapiens

Features
Gene ID: ENSG00000096063
  
Biological name :SRPK1
  
Synonyms : Q96SB4 / SRPK1 / SRSF protein kinase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.31
Gene start: 35832966
Gene end: 35921342
  
Corresponding Affymetrix probe sets: 202199_s_at (Human Genome U133 Plus 2.0 Array)   202200_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391069
Ensembl peptide - ENSP00000422886
Ensembl peptide - ENSP00000425172
Ensembl peptide - ENSP00000424323
Ensembl peptide - ENSP00000424170
Ensembl peptide - ENSP00000424068
Ensembl peptide - ENSP00000354674
Ensembl peptide - ENSP00000362931
NCBI entrez gene - 6732     See in Manteia.
OMIM - 601939
RefSeq - NM_003137
RefSeq Peptide - NP_003128
swissprot - D6RBF8
swissprot - D6RB98
swissprot - H0Y932
swissprot - H3BLV9
swissprot - D6RDZ3
swissprot - Q96SB4
swissprot - D6RBM8
Ensembl - ENSG00000096063
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srpk1aENSDARG00000073997Danio rerio
 srpk1bENSDARG00000031560Danio rerio
 SRPK1ENSGALG00000037546Gallus gallus
 Srpk1ENSMUSG00000004865Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRPK2 / P78362 / SRSF protein kinase 2ENSG0000013525060
SRPK3 / Q9UPE1 / SRSF protein kinase 3ENSG0000018434351


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035092 sperm chromatin condensation TAS
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0045070 positive regulation of viral genome replication IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IC
 biological_processGO:0048024 regulation of mRNA splicing, via spliceosome TAS
 biological_processGO:0050684 regulation of mRNA processing IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr