ENSG00000097033


Homo sapiens

Features
Gene ID: ENSG00000097033
  
Biological name :SH3GLB1
  
Synonyms : Q9Y371 / SH3 domain containing GRB2 like, endophilin B1 / SH3GLB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.3
Gene start: 86704570
Gene end: 86748184
  
Corresponding Affymetrix probe sets: 209090_s_at (Human Genome U133 Plus 2.0 Array)   209091_s_at (Human Genome U133 Plus 2.0 Array)   210101_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473267
Ensembl peptide - ENSP00000479919
Ensembl peptide - ENSP00000418744
Ensembl peptide - ENSP00000441355
NCBI entrez gene - 51100     See in Manteia.
OMIM - 609287
RefSeq - XM_017001408
RefSeq - NM_001206651
RefSeq - NM_001206652
RefSeq - NM_001206653
RefSeq - NM_016009
RefSeq - XM_006710672
RefSeq - XM_006710673
RefSeq - XM_011541538
RefSeq Peptide - NP_057093
RefSeq Peptide - NP_001193580
RefSeq Peptide - NP_001193581
RefSeq Peptide - NP_001193582
swissprot - Q9Y371
swissprot - A0A140VJU5
swissprot - A0A087WW40
Ensembl - ENSG00000097033
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3glb1aENSDARG00000045294Danio rerio
 sh3glb1bENSDARG00000010956Danio rerio
 Q5ZIR1ENSGALG00000006284Gallus gallus
 Q9JK48ENSMUSG00000037062Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NR46 / SH3GLB2 / SH3 domain containing GRB2 like, endophilin B2ENSG0000014834161
Q99961 / SH3GL1 / SH3 domain containing GRB2 like 1, endophilin A2ENSG0000014198524
Q99962 / SH3GL2 / SH3 domain containing GRB2 like 2, endophilin A1ENSG0000010729523
Q99963 / SH3GL3 / SH3 domain containing GRB2 like 3, endophilin A3ENSG0000014060022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR028503  Endophilin-B1
 IPR035695  Endophilin-B1, BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006654 phosphatidic acid biosynthetic process IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0032461 positive regulation of protein oligomerization IDA
 biological_processGO:0032465 regulation of cytokinesis IMP
 biological_processGO:0032801 receptor catabolic process IMP
 biological_processGO:0034198 cellular response to amino acid starvation IMP
 biological_processGO:0042149 cellular response to glucose starvation IMP
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IEA
 biological_processGO:0048102 autophagic cell death IMP
 biological_processGO:0051084 "de novo" posttranslational protein folding IEA
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0090148 membrane fission IMP
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway IEA
 biological_processGO:1903527 positive regulation of membrane tubulation IMP
 biological_processGO:1903778 protein localization to vacuolar membrane IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 biological_processGO:2000786 positive regulation of autophagosome assembly IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005504 fatty acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042171 lysophosphatidic acid acyltransferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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