ENSG00000105699


Homo sapiens

Features
Gene ID: ENSG00000105699
  
Biological name :LSR
  
Synonyms : lipolysis stimulated lipoprotein receptor / LSR / Q86X29
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35248330
Gene end: 35267964
  
Corresponding Affymetrix probe sets: 208190_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480821
Ensembl peptide - ENSP00000472569
Ensembl peptide - ENSP00000474797
Ensembl peptide - ENSP00000262627
Ensembl peptide - ENSP00000346976
Ensembl peptide - ENSP00000354034
Ensembl peptide - ENSP00000354575
Ensembl peptide - ENSP00000394479
Ensembl peptide - ENSP00000470630
Ensembl peptide - ENSP00000471486
Ensembl peptide - ENSP00000472154
NCBI entrez gene - 51599     See in Manteia.
OMIM - 616582
RefSeq - XM_011527026
RefSeq - NM_001260489
RefSeq - NM_001260490
RefSeq - NM_015925
RefSeq - NM_205834
RefSeq - NM_205835
RefSeq - XM_005258980
RefSeq - XM_005258982
RefSeq Peptide - NP_001247418
RefSeq Peptide - NP_001247419
RefSeq Peptide - NP_057009
RefSeq Peptide - NP_991403
RefSeq Peptide - NP_991404
swissprot - S4R3V8
swissprot - M0QZL9
swissprot - Q86X29
swissprot - M0R0W1
swissprot - M0R1W9
Ensembl - ENSG00000105699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsrENSDARG00000099291Danio rerio
 LsrENSMUSG00000001247Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ILDR2 / Q71H61 / immunoglobulin like domain containing receptor 2ENSG0000014319532
ILDR1 / Q86SU0 / immunoglobulin like domain containing receptor 1ENSG0000014510322


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008664  LISCH7
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0019216 regulation of lipid metabolic process IEA
 biological_processGO:0060856 establishment of blood-brain barrier IEA
 biological_processGO:0061833 protein localization to tricellular tight junction IEA
 biological_processGO:1904274 tricellular tight junction assembly IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IEA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0042627 chylomicron IEA
 cellular_componentGO:0061689 tricellular tight junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
LDL clearance
VLDL clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105699 LSR / Q86X29 / lipolysis stimulated lipoprotein receptor  / complex
 ENSG00000267467 APOC4 / P55056 / apolipoprotein C4  / complex / reaction
 ENSG00000130208 APOC1 / P02654 / apolipoprotein C1  / reaction / complex






 

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contact: otassy@igbmc.fr