ENSG00000110619


Homo sapiens

Features
Gene ID: ENSG00000110619
  
Biological name :CARS
  
Synonyms : CARS / cysteinyl-tRNA synthetase / P49589
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 3000922
Gene end: 3057613
  
Corresponding Affymetrix probe sets: 202402_s_at (Human Genome U133 Plus 2.0 Array)   212971_at (Human Genome U133 Plus 2.0 Array)   240982_at (Human Genome U133 Plus 2.0 Array)   240983_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000369897
Ensembl peptide - ENSP00000380300
Ensembl peptide - ENSP00000492622
Ensembl peptide - ENSP00000434184
Ensembl peptide - ENSP00000432619
Ensembl peptide - ENSP00000431368
Ensembl peptide - ENSP00000408802
Ensembl peptide - ENSP00000278224
NCBI entrez gene - 833     See in Manteia.
OMIM - 123859
RefSeq - XM_006718341
RefSeq - XM_017018392
RefSeq - XM_017018391
RefSeq - XM_017018390
RefSeq - XM_017018389
RefSeq - NM_001014437
RefSeq - NM_001194997
RefSeq - NM_001751
RefSeq - NM_139273
RefSeq Peptide - NP_001014437
RefSeq Peptide - NP_001181926
RefSeq Peptide - NP_001742
RefSeq Peptide - NP_644802
swissprot - P49589
swissprot - E9PRS8
swissprot - A0A024RCG3
swissprot - B4DKY1
swissprot - C9JLN0
swissprot - E9PLP0
Ensembl - ENSG00000110619
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 carsENSDARG00000036164Danio rerio
 CARSENSGALG00000006427Gallus gallus
 CarsENSMUSG00000010755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CARS2 / Q9HA77 / cysteinyl-tRNA synthetase 2, mitochondrialENSG0000013490524


Protein motifs (from Interpro)
Interpro ID Name
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR015803  Cysteine-tRNA ligase
 IPR024909  Cysteinyl-tRNA synthetase/mycothiol ligase
 IPR032678  tRNA synthetases class I, catalytic domain
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006423 cysteinyl-tRNA aminoacylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000049 tRNA binding NAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004817 cysteine-tRNA ligase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IMP
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cytosolic tRNA aminoacylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110619 CARS / P49589 / cysteinyl-tRNA synthetase  / complex






 

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