ENSG00000115561


Homo sapiens

Features
Gene ID: ENSG00000115561
  
Biological name :CHMP3
  
Synonyms : charged multivesicular body protein 3 / CHMP3 / Q9Y3E7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p11.2
Gene start: 86503431
Gene end: 86563479
  
Corresponding Affymetrix probe sets: 217837_s_at (Human Genome U133 Plus 2.0 Array)   222436_s_at (Human Genome U133 Plus 2.0 Array)   222437_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263856
Ensembl peptide - ENSP00000386590
Ensembl peptide - ENSP00000387045
NCBI entrez gene - 51652     See in Manteia.
OMIM - 610052
RefSeq - NM_001193517
RefSeq - NM_001005753
RefSeq - NM_016079
RefSeq Peptide - NP_001005753
RefSeq Peptide - NP_001180446
RefSeq Peptide - NP_057163
swissprot - Q9Y3E7
Ensembl - ENSG00000115561
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chmp3ENSDARG00000038064Danio rerio
 ENSGALG00000015805Gallus gallus
 Chmp3ENSMUSG00000053119Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RNF103-CHMP3 / RNF103-CHMP3 readthroughENSG0000024988495


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000920 cell separation after cytokinesis IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0019058 viral life cycle TAS
 biological_processGO:0036258 multivesicular body assembly TAS
 biological_processGO:0039702 viral budding via host ESCRT complex IMP
 biological_processGO:0050792 regulation of viral process IMP
 biological_processGO:0051258 protein polymerization IDA
 biological_processGO:0051291 protein heterooligomerization IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0061763 multivesicular body-lysosome fusion IMP
 biological_processGO:0071985 multivesicular body sorting pathway TAS
 biological_processGO:0097352 autophagosome maturation TAS
 biological_processGO:1902187 negative regulation of viral release from host cell IMP
 biological_processGO:1902188 positive regulation of viral release from host cell IMP
 biological_processGO:2000641 regulation of early endosome to late endosome transport IMP
 cellular_componentGO:0000815 ESCRT III complex IDA
 cellular_componentGO:0005622 intracellular IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031210 phosphatidylcholine binding IMP
 molecular_functionGO:0042803 protein homodimerization activity IMP
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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