ENSG00000125450


Homo sapiens

Features
Gene ID: ENSG00000125450
  
Biological name :NUP85
  
Synonyms : nucleoporin 85 / NUP85 / Q9BW27
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 75205659
Gene end: 75235758
  
Corresponding Affymetrix probe sets: 218014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464544
Ensembl peptide - ENSP00000463715
Ensembl peptide - ENSP00000464433
Ensembl peptide - ENSP00000245544
Ensembl peptide - ENSP00000445855
Ensembl peptide - ENSP00000461919
Ensembl peptide - ENSP00000462364
Ensembl peptide - ENSP00000462487
Ensembl peptide - ENSP00000462749
Ensembl peptide - ENSP00000462920
Ensembl peptide - ENSP00000463377
Ensembl peptide - ENSP00000463382
Ensembl peptide - ENSP00000463437
Ensembl peptide - ENSP00000463496
Ensembl peptide - ENSP00000463542
NCBI entrez gene - 79902     See in Manteia.
OMIM - 170285
RefSeq - XM_017025110
RefSeq - NM_001303276
RefSeq - NM_024844
RefSeq - XM_005257692
RefSeq - XM_006722094
RefSeq - XM_011525267
RefSeq - XM_017025108
RefSeq - XM_017025109
RefSeq Peptide - NP_001317401
RefSeq Peptide - NP_079120
RefSeq Peptide - NP_001290205
swissprot - J3QLV0
swissprot - J3QRY3
swissprot - J3QS63
swissprot - Q9BW27
swissprot - F5H0W7
swissprot - J3KRC0
swissprot - J3KS87
swissprot - J3KSH3
swissprot - J3KT10
swissprot - J3KTC7
swissprot - J3QL49
swissprot - J3QL91
swissprot - J3QL54
swissprot - J3QLD4
swissprot - J3QLH0
Ensembl - ENSG00000125450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nucleoporin 85ENSDARG00000112002Danio rerio
 nup85ENSDARG00000098679Danio rerio
 NUP85ENSGALG00000007974Gallus gallus
 Nup85ENSMUSG00000020739Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011502  Nucleoporin Nup85-like
 IPR011990  Tetratricopeptide-like helical domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0048246 macrophage chemotaxis IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031080 nuclear pore outer ring NAS
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017056 structural constituent of nuclear pore IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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