ENSG00000125691


Homo sapiens

Features
Gene ID: ENSG00000125691
  
Biological name :RPL23
  
Synonyms : P62829 / ribosomal protein L23 / RPL23
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 38847865
Gene end: 38853843
  
Corresponding Affymetrix probe sets: 200888_s_at (Human Genome U133 Plus 2.0 Array)   214744_s_at (Human Genome U133 Plus 2.0 Array)   215224_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377866
Ensembl peptide - ENSP00000420311
Ensembl peptide - ENSP00000463894
Ensembl peptide - ENSP00000463014
Ensembl peptide - ENSP00000462773
Ensembl peptide - ENSP00000367336
Ensembl peptide - ENSP00000377865
NCBI entrez gene - 9349     See in Manteia.
OMIM - 603662
RefSeq - NM_000978
RefSeq Peptide - NP_000969
swissprot - A0A024R1Q8
swissprot - J3KT29
swissprot - J3KTJ3
swissprot - J3QQT9
swissprot - C9JD32
swissprot - P62829
swissprot - B9ZVP7
Ensembl - ENSG00000125691
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl23ENSDARG00000053457Danio rerio
 RPL23ENSGALG00000001634Gallus gallus
 Rpl23ENSMUSG00000071415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000218  Ribosomal protein L14P
 IPR019972  Ribosomal protein L14P, conserved site
 IPR036853  Ribosomal protein L14 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006610 ribosomal protein import into nucleus NAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0032986 protein-DNA complex disassembly IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0071157 negative regulation of cell cycle arrest IMP
 biological_processGO:0071158 positive regulation of cell cycle arrest IMP
 biological_processGO:0072717 cellular response to actinomycin D IMP
 biological_processGO:1901798 positive regulation of signal transduction by p53 class mediator IMP
 biological_processGO:1904667 negative regulation of ubiquitin protein ligase activity IDA
 biological_processGO:2000059 negative regulation of ubiquitin-dependent protein catabolic process IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit HDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0070180 large ribosomal subunit rRNA binding IBA
 molecular_functionGO:1990948 ubiquitin ligase inhibitor activity IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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