ENSG00000125878


Homo sapiens

Features
Gene ID: ENSG00000125878
  
Biological name :TCF15
  
Synonyms : Q12870 / TCF15 / transcription factor 15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 603797
Gene end: 610398
  
Corresponding Affymetrix probe sets: 207306_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000246080
NCBI entrez gene - 6939     See in Manteia.
OMIM - 601010
RefSeq - NM_004609
RefSeq Peptide - NP_004600
swissprot - Q12870
Ensembl - ENSG00000125878
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TCF15ENSGALG00000026276Gallus gallus
 Tcf15ENSMUSG00000068079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCX / Q7RTU7 / scleraxis bHLH transcription factorENSG0000026042855
TAL1 / P17542 / TAL bHLH transcription factor 1, erythroid differentiation factorENSG0000016236729
LYL1 / P12980 / LYL1, basic helix-loop-helix family memberENSG0000010490326
Q8WVJ9 / TWIST2 / twist family bHLH transcription factor 2ENSG0000023360824
Q15672 / TWIST1 / twist family bHLH transcription factor 1ENSG0000012269124
HAND1 / O96004 / heart and neural crest derivatives expressed 1ENSG0000011319623
HAND2 / P61296 / heart and neural crest derivatives expressed 2ENSG0000016410722
NHLH1 / Q02575 / nescient helix-loop-helix 1ENSG0000017178618
NHLH2 / Q02577 / nescient helix-loop-helix 2ENSG0000017755118
TAL2 / Q16559 / TAL bHLH transcription factor 2ENSG0000018605118


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007498 mesoderm development TAS
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0036342 post-anal tail morphogenesis IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0043583 ear development IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048339 paraxial mesoderm development IEA
 biological_processGO:0048644 muscle organ morphogenesis IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0050884 neuromuscular process controlling posture IEA
 biological_processGO:0060231 mesenchymal to epithelial transition IEA
 biological_processGO:1903053 regulation of extracellular matrix organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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