ENSG00000130770


Homo sapiens

Features
Gene ID: ENSG00000130770
  
Biological name :ATP5IF1
  
Synonyms : ATP5IF1 / ATP synthase inhibitory factor subunit 1 / Q9UII2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28236109
Gene end: 28246906
  
Corresponding Affymetrix probe sets: 218671_s_at (Human Genome U133 Plus 2.0 Array)   223338_s_at (Human Genome U133 Plus 2.0 Array)   223339_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437337
Ensembl peptide - ENSP00000335203
Ensembl peptide - ENSP00000435341
Ensembl peptide - ENSP00000435579
NCBI entrez gene - 93974     See in Manteia.
OMIM - 614981
RefSeq - NM_016311
RefSeq - NM_178190
RefSeq - NM_178191
RefSeq Peptide - NP_057395
RefSeq Peptide - NP_835497
RefSeq Peptide - NP_835498
swissprot - Q9UII2
swissprot - A0A0B4J230
Ensembl - ENSG00000130770
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A3KNL5ENSDARG00000067975Danio rerio
 Q1LYB6ENSDARG00000044092Danio rerio
 ATP5IF1ENSGALG00000038672Gallus gallus
 Atpif1ENSMUSG00000054428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007648  Mitochondrial ATPase inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IDA
 biological_processGO:0006091 generation of precursor metabolites and energy TAS
 biological_processGO:0006783 heme biosynthetic process IMP
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0032780 negative regulation of ATPase activity IMP
 biological_processGO:0051260 protein homooligomerization ISS
 biological_processGO:0051289 protein homotetramerization ISS
 biological_processGO:0051346 negative regulation of hydrolase activity ISS
 biological_processGO:0051882 mitochondrial depolarization IMP
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IEA
 biological_processGO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process IMP
 biological_processGO:1903214 regulation of protein targeting to mitochondrion IMP
 biological_processGO:1903578 regulation of ATP metabolic process IMP
 biological_processGO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization IMP
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005753 mitochondrial proton-transporting ATP synthase complex IDA
 cellular_componentGO:0009986 cell surface IDA
 molecular_functionGO:0004857 enzyme inhibitor activity TAS
 molecular_functionGO:0005516 calmodulin binding ISS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042030 ATPase inhibitor activity IMP
 molecular_functionGO:0042803 protein homodimerization activity TAS
 molecular_functionGO:0043532 angiostatin binding IDA
 molecular_functionGO:0051117 ATPase binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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