ENSG00000130812
Homo sapiens | |
Features See expression report in BioGPS See gene description in Wikigenes See gene description in GeneCards See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
Protein motifs (from Interpro)
IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | IPR014715 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2 | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | IPR020837 | Fibrinogen, conserved site | IPR036056 | Fibrinogen-like, C-terminal |
Gene Ontology (GO)
Pathways (from Reactome) No match
Phenotype (from MGI, Zfin or HPO)
HP:0000822 | Hypertension | "High blood pressure." [HPO:curators] |
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| HP:0001123 | Visual field defects | |
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| HP:0001250 | Seizures | "Seizures are an intermittent `abnormality of the central nervous system` (FMA:HP:0002011) due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements." [HPO:probinson] |
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| HP:0001269 | Hemiparesis | "Relatively mild weakness in the arm, leg, and in some cases the face on one side of the body." [HPO:curators] |
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| HP:0002138 | Subarachnoid hemorrhage | |
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| HP:0002326 | Transient ischemic attack | |
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| HP:0002363 | Abnormality of the brainstem | |
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| HP:0002616 | Aortic root dilatation | |
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| HP:0002621 | Atherosclerosis | "A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls of medium-sized and large arteries and can lead to arterial stenosis with reduced or blocked blood flow." [HPO:curators] |
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| HP:0002647 | Aortic dissection | "Aortic dissection refers to a tear in the intimal layer of the aorta causing a separation between the intima and the medial layers of the aorta." [HPO:curators] |
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| HP:0007029 | Cerebral berry aneurysms | |
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| HP:0012246 | Oculomotor nerve palsy | "Reduced ability to control the movement of the eye associated with damage to the third cranial nerve (the oculomotor nerve)." [HPO:probinson] |
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| HP:0012518 | Abnormality of circle of Willis | "An anomaly of the `circle of Willis` (FMA:50454), also known as the cerebral arterial circle." [HPO:probinson] |
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| HP:0040197 | Encephalomalacia | "Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury." [PhenoTips:CHum] |
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Interacting proteins (from Reactome) No match
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