ENSG00000137054


Homo sapiens

Features
Gene ID: ENSG00000137054
  
Biological name :POLR1E
  
Synonyms : POLR1E / Q9GZS1 / RNA polymerase I subunit E
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.2
Gene start: 37485935
Gene end: 37503697
  
Corresponding Affymetrix probe sets: 1568997_at (Human Genome U133 Plus 2.0 Array)   218997_at (Human Genome U133 Plus 2.0 Array)   231041_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000399887
Ensembl peptide - ENSP00000367023
Ensembl peptide - ENSP00000367029
NCBI entrez gene - 64425     See in Manteia.
RefSeq - XM_005251547
RefSeq - NM_001282766
RefSeq - NM_022490
RefSeq Peptide - NP_001269695
RefSeq Peptide - NP_071935
swissprot - Q9GZS1
swissprot - E7EX70
Ensembl - ENSG00000137054
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr1eENSDARG00000006434Danio rerio
 POLR1EENSGALG00000005395Gallus gallus
 Polr1eENSMUSG00000028318Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009668  RNA polymerase I associated factor, A49-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter TAS
 biological_processGO:0006363 termination of RNA polymerase I transcription TAS
 biological_processGO:0045815 positive regulation of gene expression, epigenetic TAS
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IBA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0001179 RNA polymerase I transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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