ENSG00000137814


Homo sapiens

Features
Gene ID: ENSG00000137814
  
Biological name :HAUS2
  
Synonyms : HAUS2 / HAUS augmin like complex subunit 2 / Q9NVX0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q15.2
Gene start: 42548810
Gene end: 42569994
  
Corresponding Affymetrix probe sets: 220071_x_at (Human Genome U133 Plus 2.0 Array)   228744_at (Human Genome U133 Plus 2.0 Array)   229181_s_at (Human Genome U133 Plus 2.0 Array)   229208_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475909
Ensembl peptide - ENSP00000475743
Ensembl peptide - ENSP00000491926
Ensembl peptide - ENSP00000260372
Ensembl peptide - ENSP00000390445
Ensembl peptide - ENSP00000455104
Ensembl peptide - ENSP00000455118
Ensembl peptide - ENSP00000455942
Ensembl peptide - ENSP00000456054
Ensembl peptide - ENSP00000456578
Ensembl peptide - ENSP00000457169
NCBI entrez gene - 55142     See in Manteia.
OMIM - 613429
RefSeq - XM_017022397
RefSeq - NM_001130447
RefSeq - NM_001323629
RefSeq - NM_001323630
RefSeq - NM_001323631
RefSeq - NM_001323632
RefSeq - NM_018097
RefSeq - XM_017022396
RefSeq Peptide - NP_001310560
RefSeq Peptide - NP_060567
RefSeq Peptide - NP_001123919
RefSeq Peptide - NP_001310558
RefSeq Peptide - NP_001310559
RefSeq Peptide - NP_001310561
swissprot - H3BTG9
swissprot - J3QT48
swissprot - H3BP16
swissprot - H3BP24
swissprot - H3BQU2
swissprot - Q9NVX0
swissprot - U3KQI5
swissprot - A0A024R9P0
swissprot - H3BR32
Ensembl - ENSG00000137814
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-170l10.1ENSDARG00000036781Danio rerio
 HAUS2ENSGALG00000009111Gallus gallus
 Haus2ENSMUSG00000027285Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026242  HAUS augmin-like complex subunit 2, metazoa
 IPR028346  HAUS augmin-like complex subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0031023 microtubule organizing center organization IEA
 biological_processGO:0051225 spindle assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 cellular_componentGO:0070652 HAUS complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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