ENSG00000139350


Homo sapiens

Features
Gene ID: ENSG00000139350
  
Biological name :NEDD1
  
Synonyms : NEDD1 / neural precursor cell expressed, developmentally down-regulated 1 / Q8NHV4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.1
Gene start: 96907223
Gene end: 96953777
  
Corresponding Affymetrix probe sets: 1552417_a_at (Human Genome U133 Plus 2.0 Array)   1560116_a_at (Human Genome U133 Plus 2.0 Array)   234984_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451830
Ensembl peptide - ENSP00000451211
Ensembl peptide - ENSP00000451869
Ensembl peptide - ENSP00000266742
Ensembl peptide - ENSP00000404978
Ensembl peptide - ENSP00000407964
Ensembl peptide - ENSP00000411307
Ensembl peptide - ENSP00000450757
Ensembl peptide - ENSP00000450828
Ensembl peptide - ENSP00000450881
NCBI entrez gene - 121441     See in Manteia.
OMIM - 600372
RefSeq - XM_017018802
RefSeq - NM_001135175
RefSeq - NM_001135176
RefSeq - NM_001135177
RefSeq - NM_152905
RefSeq - XM_005268644
RefSeq - XM_006719237
RefSeq - XM_011537903
RefSeq - XM_011537904
RefSeq - XM_011537905
RefSeq - XM_011537906
RefSeq - XM_017018801
RefSeq Peptide - NP_001128648
RefSeq Peptide - NP_001128649
RefSeq Peptide - NP_690869
RefSeq Peptide - NP_001128647
swissprot - G3V4L2
swissprot - A0A024RBE5
swissprot - G3V2M9
swissprot - Q8NHV4
swissprot - G3V2S2
swissprot - G3V2V3
swissprot - G3V4I9
Ensembl - ENSG00000139350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nedd1ENSDARG00000013472Danio rerio
 NEDD1ENSGALG00000031699Gallus gallus
 Nedd1ENSMUSG00000019988Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071539 protein localization to centrosome IBA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0000242 pericentriolar material IBA
 cellular_componentGO:0000922 spindle pole IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005814 centriole IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0036064 ciliary basal body IBA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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