ENSG00000140750


Homo sapiens

Features
Gene ID: ENSG00000140750
  
Biological name :ARHGAP17
  
Synonyms : ARHGAP17 / Q68EM7 / Rho GTPase activating protein 17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.1
Gene start: 24919385
Gene end: 25015666
  
Corresponding Affymetrix probe sets: 218076_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461426
Ensembl peptide - ENSP00000461411
Ensembl peptide - ENSP00000461639
Ensembl peptide - ENSP00000289968
Ensembl peptide - ENSP00000303130
Ensembl peptide - ENSP00000406701
Ensembl peptide - ENSP00000459074
Ensembl peptide - ENSP00000460600
Ensembl peptide - ENSP00000460985
NCBI entrez gene - 55114     See in Manteia.
OMIM - 608293
RefSeq - XM_017023390
RefSeq - NM_001006634
RefSeq - NM_018054
RefSeq - XM_011545873
RefSeq - XM_011545874
RefSeq - XM_011545875
RefSeq - XM_011545876
RefSeq - XM_011545877
RefSeq - XM_011545878
RefSeq Peptide - NP_001006635
RefSeq Peptide - NP_060524
swissprot - I3L1S9
swissprot - I3L3P1
swissprot - I3L460
swissprot - I3L4P0
swissprot - I3L4P6
swissprot - I3L4Y5
swissprot - Q68EM7
swissprot - C9IZD3
Ensembl - ENSG00000140750
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap17aENSDARG00000020488Danio rerio
 arhgap17bENSDARG00000062263Danio rerio
 ARHGAP17ENSGALG00000041213Gallus gallus
 Q3UIA2ENSMUSG00000030766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG0000000674045
Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1ENSG0000010009235
Z83844.3ENSG0000028530426
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622017
Q7Z5H3 / ARHGAP22 / Rho GTPase activating protein 22ENSG0000012880515
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693515
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982015
P42331 / ARHGAP25 / Rho GTPase activating protein 25ENSG0000016321914
Q8N264 / ARHGAP24 / Rho GTPase activating protein 24ENSG0000013863914
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602814
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG000001719434
P0DMP2 / SRGAP2B / SLIT-ROBO Rho GTPase activating protein 2BENSG000001963692


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR004148  BAR domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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