ENSG00000140988


Homo sapiens

Features
Gene ID: ENSG00000140988
  
Biological name :RPS2
  
Synonyms : P15880 / ribosomal protein S2 / RPS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 1962052
Gene end: 1964860
  
Corresponding Affymetrix probe sets: 203107_x_at (Human Genome U133 Plus 2.0 Array)   212433_x_at (Human Genome U133 Plus 2.0 Array)   217466_x_at (Human Genome U133 Plus 2.0 Array)   221798_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434846
Ensembl peptide - ENSP00000436227
Ensembl peptide - ENSP00000460860
Ensembl peptide - ENSP00000454837
Ensembl peptide - ENSP00000436865
Ensembl peptide - ENSP00000436356
Ensembl peptide - ENSP00000341885
Ensembl peptide - ENSP00000433034
Ensembl peptide - ENSP00000433170
NCBI entrez gene - 6187     See in Manteia.
OMIM - 603624
RefSeq - NM_002952
RefSeq Peptide - NP_002943
swissprot - E9PMM9
swissprot - E9PM36
swissprot - H0YE27
swissprot - H0YEN5
swissprot - H3BNG3
swissprot - I3L404
swissprot - E9PQD7
swissprot - P15880
swissprot - E9PPT0
Ensembl - ENSG00000140988
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps2ENSDARG00000077291Danio rerio
 RPS2ENSGALG00000005490Gallus gallus
 Gm8225ENSMUSG00000068604Mus musculus
 Rps2ENSMUSG00000044533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000851  Ribosomal protein S5
 IPR005324  Ribosomal protein S5, C-terminal
 IPR005711  Ribosomal protein S5, eukaryotic/archaeal
 IPR013810  Ribosomal protein S5, N-terminal
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR018192  Ribosomal protein S5, N-terminal, conserved site
 IPR020568  Ribosomal protein S5 domain 2-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006479 protein methylation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IDA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015935 small ribosomal subunit IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017134 fibroblast growth factor binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
RMTs methylate histone arginines
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Protein methylation
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185238 PRMT3 / O60678 / protein arginine methyltransferase 3  / reaction






 

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contact: otassy@igbmc.fr