ENSG00000148303


Homo sapiens

Features
Gene ID: ENSG00000148303
  
Biological name :RPL7A
  
Synonyms : P62424 / ribosomal protein L7a / RPL7A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.2
Gene start: 133348214
Gene end: 133351426
  
Corresponding Affymetrix probe sets: 217740_x_at (Human Genome U133 Plus 2.0 Array)   224930_x_at (Human Genome U133 Plus 2.0 Array)   234873_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361071
Ensembl peptide - ENSP00000361076
Ensembl peptide - ENSP00000416638
NCBI entrez gene - 6130     See in Manteia.
OMIM - 185640
RefSeq - NM_000972
RefSeq Peptide - NP_000963
swissprot - P62424
swissprot - Q5T8U2
swissprot - Q5T8U3
Ensembl - ENSG00000148303
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl7aENSDARG00000019230Danio rerio
 RPL7AENSGALG00000003197Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001921  Ribosomal protein L7A/L8
 IPR004037  Ribosomal protein L7Ae conserved site
 IPR004038  Ribosomal protein L7Ae/L30e/S12e/Gadd45
 IPR018492  Ribosomal protein L7Ae/L8/Nhp2 family
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0000470 maturation of LSU-rRNA IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IBA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0042254 ribosome biogenesis IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005730 nucleolus HDA
 cellular_componentGO:0005737 cytoplasm HDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0042788 polysomal ribosome IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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