ENSG00000149100


Homo sapiens

Features
Gene ID: ENSG00000149100
  
Biological name :EIF3M
  
Synonyms : EIF3M / eukaryotic translation initiation factor 3 subunit M / Q7L2H7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p13
Gene start: 32583798
Gene end: 32606262
  
Corresponding Affymetrix probe sets: 202231_at (Human Genome U133 Plus 2.0 Array)   202232_s_at (Human Genome U133 Plus 2.0 Array)   215190_at (Human Genome U133 Plus 2.0 Array)   239848_at (Human Genome U133 Plus 2.0 Array)   240513_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432286
Ensembl peptide - ENSP00000436787
Ensembl peptide - ENSP00000436049
Ensembl peptide - ENSP00000435834
Ensembl peptide - ENSP00000435501
Ensembl peptide - ENSP00000434080
Ensembl peptide - ENSP00000432891
Ensembl peptide - ENSP00000319910
Ensembl peptide - ENSP00000432139
NCBI entrez gene - 10480     See in Manteia.
OMIM - 609641
RefSeq - NM_001307929
RefSeq - NM_006360
RefSeq - XM_011519840
RefSeq Peptide - NP_001294858
RefSeq Peptide - NP_006351
swissprot - E9PSB3
swissprot - Q7L2H7
swissprot - J3KNJ2
swissprot - E9PRY0
swissprot - E9PRI2
swissprot - E9PN86
swissprot - E7ESM3
swissprot - H0YCQ8
Ensembl - ENSG00000149100
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3mENSDARG00000013931Danio rerio
 EIF3MENSGALG00000012109Gallus gallus
 Eif3mENSMUSG00000027170Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR027528  Eukaryotic translation initiation factor 3 subunit M
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002183 cytoplasmic translational initiation IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IEA
 molecular_functionGO:0003743 translation initiation factor activity IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031369 translation initiation factor binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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