ENSG00000149823


Homo sapiens

Features
Gene ID: ENSG00000149823
  
Biological name :VPS51
  
Synonyms : Q9UID3 / VPS51 / VPS51, GARP complex subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.1
Gene start: 65089324
Gene end: 65111860
  
Corresponding Affymetrix probe sets: 217969_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431317
Ensembl peptide - ENSP00000433579
Ensembl peptide - ENSP00000492351
Ensembl peptide - ENSP00000436867
Ensembl peptide - ENSP00000436134
Ensembl peptide - ENSP00000435691
Ensembl peptide - ENSP00000435629
Ensembl peptide - ENSP00000435245
Ensembl peptide - ENSP00000434542
Ensembl peptide - ENSP00000434138
Ensembl peptide - ENSP00000279281
Ensembl peptide - ENSP00000431188
NCBI entrez gene - 738     See in Manteia.
OMIM - 615738
RefSeq - NM_013265
RefSeq Peptide - NP_037397
swissprot - E9PQD5
swissprot - E9PMB6
swissprot - E9PKX7
swissprot - E9PKE5
swissprot - E9PJ36
swissprot - A0A1W2PQZ2
swissprot - H0YCB7
swissprot - H0YDX9
swissprot - H0YEE1
swissprot - E9PRV0
swissprot - Q9UID3
swissprot - E9PQN6
Ensembl - ENSG00000149823
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps51ENSDARG00000062016Danio rerio
 VPS51ENSGALG00000004166Gallus gallus
 Q3UVL4ENSMUSG00000024799Mus musculus
 Vps51ENSMUSG00000024797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007255  Conserved oligomeric Golgi complex subunit 8
 IPR014812  Vacuolar protein sorting-associated protein 51
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0007041 lysosomal transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032456 endocytic recycling IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0048193 Golgi vesicle transport IBA
 cellular_componentGO:0000938 GARP complex IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0017119 Golgi transport complex IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:1990745 EARP complex IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000003056 M6PR / P20645 / mannose-6-phosphate receptor, cation dependent  / reaction
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / reaction
 ENSG00000123595 RAB9A / P51151 / RAB9A, member RAS oncogene family  / reaction
 ENSG00000104915 STX10 / O60499 / syntaxin 10  / reaction
 ENSG00000136933 Q7Z6M1 / RABEPK / Rab9 effector protein with kelch motifs  / reaction
 ENSG00000141252 VPS53 / Q5VIR6 / VPS53, GARP complex subunit  / complex
 ENSG00000143952 VPS54 / Q9P1Q0 / VPS54, GARP complex subunit  / complex
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / reaction
 ENSG00000135968 GCC2 / Q8IWJ2 / GRIP and coiled-coil domain containing 2  / reaction
 ENSG00000197081 IGF2R / P11717 / insulin like growth factor 2 receptor  / reaction
 ENSG00000151532 VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A  / reaction
 ENSG00000223501 VPS52 / Q8N1B4 / VPS52, GARP complex subunit  / complex






 

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contact: otassy@igbmc.fr