ENSG00000160633


Homo sapiens

Features
Gene ID: ENSG00000160633
  
Biological name :SAFB
  
Synonyms : Q15424 / SAFB / scaffold attachment factor B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 5623035
Gene end: 5668478
  
Corresponding Affymetrix probe sets: 201747_s_at (Human Genome U133 Plus 2.0 Array)   201748_s_at (Human Genome U133 Plus 2.0 Array)   213635_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468543
Ensembl peptide - ENSP00000464840
Ensembl peptide - ENSP00000467423
Ensembl peptide - ENSP00000292123
Ensembl peptide - ENSP00000415895
Ensembl peptide - ENSP00000464758
NCBI entrez gene - 6294     See in Manteia.
OMIM - 602895
RefSeq - XM_017027118
RefSeq - NM_001201339
RefSeq - NM_001201340
RefSeq - NM_001320571
RefSeq - NM_001320572
RefSeq - NM_002967
RefSeq - XM_017027114
RefSeq - XM_017027115
RefSeq - XM_017027116
RefSeq - XM_017027117
RefSeq - NM_001201338
RefSeq Peptide - NP_001188268
RefSeq Peptide - NP_001188269
RefSeq Peptide - NP_001307500
RefSeq Peptide - NP_001307501
RefSeq Peptide - NP_002958
RefSeq Peptide - NP_001188267
swissprot - K7EII0
swissprot - K7ES42
swissprot - Q15424
Ensembl - ENSG00000160633
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 safbENSDARG00000020467Danio rerio
 ENSGALG00000013365Gallus gallus
 ENSGALG00000001948Gallus gallus
 SafbENSMUSG00000071054Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SAFB2 / Q14151 / scaffold attachment factor B2ENSG0000013025470
SLTM / Q9NWH9 / SAFB like transcription modulatorENSG0000013777630


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR003034  SAP domain
 IPR034781  Scaffold attachment factor B1
 IPR035979  RNA-binding domain superfamily
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0040007 growth IEA
 biological_processGO:0042445 hormone metabolic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050684 regulation of mRNA processing IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / reaction / complex
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction
 ENSG00000188612 SUMO2 / P61956 / small ubiquitin-like modifier 2  / reaction
 ENSG00000184900 SUMO3 / P55854 / small ubiquitin-like modifier 3  / reaction






 

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