ENSG00000163029


Homo sapiens

Features
Gene ID: ENSG00000163029
  
Biological name :SMC6
  
Synonyms : Q96SB8 / SMC6 / structural maintenance of chromosomes 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p24.2
Gene start: 17663812
Gene end: 17800242
  
Corresponding Affymetrix probe sets: 218781_at (Human Genome U133 Plus 2.0 Array)   236535_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384539
Ensembl peptide - ENSP00000404092
Ensembl peptide - ENSP00000480257
Ensembl peptide - ENSP00000415352
Ensembl peptide - ENSP00000412246
Ensembl peptide - ENSP00000408644
Ensembl peptide - ENSP00000323439
Ensembl peptide - ENSP00000370672
NCBI entrez gene - 79677     See in Manteia.
OMIM - 609387
RefSeq - XM_011533108
RefSeq - XM_011533107
RefSeq - XM_017004915
RefSeq - XM_017004914
RefSeq - XM_017004913
RefSeq - NM_001142286
RefSeq - NM_024624
RefSeq - XM_017004916
RefSeq Peptide - NP_078900
RefSeq Peptide - NP_001135758
swissprot - Q96SB8
swissprot - C9JMN1
swissprot - H7C3J8
swissprot - A0A087WWI9
swissprot - A0A0A0MRY1
swissprot - C9JEF0
Ensembl - ENSG00000163029
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smc6ENSDARG00000091821Danio rerio
 SMC6ENSGALG00000016467Gallus gallus
 Smc6ENSMUSG00000020608Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR027132  Structural maintenance of chromosomes protein 6
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000722 telomere maintenance via recombination IMP
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0051984 positive regulation of chromosome segregation IMP
 biological_processGO:0090398 cellular senescence IMP
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000803 sex chromosome ISS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030915 Smc5-Smc6 complex IEA
 cellular_componentGO:0035061 interchromatin granule IDA
 cellular_componentGO:0035861 site of double-strand break IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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