ENSG00000167553


Homo sapiens

Features
Gene ID: ENSG00000167553
  
Biological name :TUBA1C
  
Synonyms : Q9BQE3 / TUBA1C / tubulin alpha 1c
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.12
Gene start: 49188736
Gene end: 49274603
  
Corresponding Affymetrix probe sets: 209251_x_at (Human Genome U133 Plus 2.0 Array)   211750_x_at (Human Genome U133 Plus 2.0 Array)   212639_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448646
Ensembl peptide - ENSP00000447910
Ensembl peptide - ENSP00000447669
Ensembl peptide - ENSP00000443475
Ensembl peptide - ENSP00000301072
Ensembl peptide - ENSP00000492176
Ensembl peptide - ENSP00000448211
NCBI entrez gene - 84790     See in Manteia.
RefSeq - NM_032704
RefSeq - NM_001303114
RefSeq - NM_001303115
RefSeq - NM_001303116
RefSeq - NM_001303117
RefSeq Peptide - NP_001290043
RefSeq Peptide - NP_116093
RefSeq Peptide - NP_001290046
RefSeq Peptide - NP_001290045
RefSeq Peptide - NP_001290044
swissprot - Q9BQE3
swissprot - A0A1W2PQM2
swissprot - F5H5D3
swissprot - F8VRK1
swissprot - F8VS66
swissprot - H0YHV2
Ensembl - ENSG00000167553
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TUBA1CENSGALG00000040260Gallus gallus
 AC161165.4ENSMUSG00000116358Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P68363 / TUBA1B / tubulin alpha 1bENSG0000012341685
Q71U36 / TUBA1A / tubulin alpha 1aENSG0000016755285
P68366 / TUBA4A / tubulin alpha 4aENSG0000012782483
Q13748 / TUBA3C / tubulin alpha 3cENSG0000019803383
Q13748 / TUBA3D / tubulin alpha 3dENSG0000007588683
Q6PEY2 / TUBA3E / tubulin alpha 3eENSG0000015208682
Q9H853 / TUBA4B / tubulin alpha 4bENSG0000024391034


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002452  Alpha tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport TAS
 biological_processGO:0051301 cell division TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0031982 vesicle HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005198 structural molecule activity TAS
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Hedgehog off state
Cilium Assembly
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr