ENSG00000170385


Homo sapiens

Features
Gene ID: ENSG00000170385
  
Biological name :SLC30A1
  
Synonyms : Q9Y6M5 / SLC30A1 / solute carrier family 30 member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.3
Gene start: 211571568
Gene end: 211578742
  
Corresponding Affymetrix probe sets: 212907_at (Human Genome U133 Plus 2.0 Array)   228181_at (Human Genome U133 Plus 2.0 Array)   242716_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355968
NCBI entrez gene - 7779     See in Manteia.
OMIM - 609521
RefSeq - NM_021194
RefSeq Peptide - NP_067017
swissprot - Q9Y6M5
Ensembl - ENSG00000170385
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc30a1aENSDARG00000005463Danio rerio
 slc30a1bENSDARG00000053896Danio rerio
 SLC30A1ENSGALG00000009858Gallus gallus
 Q60738ENSMUSG00000037434Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6XR72 / SLC30A10 / solute carrier family 30 member 10ENSG0000019666034
Q99726 / SLC30A3 / solute carrier family 30 member 3ENSG0000011519418
Q9BRI3 / SLC30A2 / solute carrier family 30 member 2ENSG0000015801418
Q8IWU4 / SLC30A8 / solute carrier family 30 member 8ENSG0000016475617
O14863 / SLC30A4 / solute carrier family 30 member 4ENSG0000010415416


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027469  Cation efflux transmembrane domain superfamily
 IPR036837  Cation efflux protein, cytoplasmic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006829 zinc ion transport ISS
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0006882 cellular zinc ion homeostasis IEA
 biological_processGO:0010043 response to zinc ion IBA
 biological_processGO:0046929 negative regulation of neurotransmitter secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061088 regulation of sequestering of zinc ion IBA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070509 calcium ion import IEA
 biological_processGO:0070574 cadmium ion transmembrane transport IEA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0071584 negative regulation of zinc ion transmembrane import IEA
 biological_processGO:0071585 detoxification of cadmium ion IEA
 biological_processGO:0090281 negative regulation of calcium ion import IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Zinc efflux and compartmentalization by the SLC30 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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