ENSG00000170515


Homo sapiens

Features
Gene ID: ENSG00000170515
  
Biological name :PA2G4
  
Synonyms : PA2G4 / proliferation-associated 2G4 / Q9UQ80
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.2
Gene start: 56104319
Gene end: 56113907
  
Corresponding Affymetrix probe sets: 208676_s_at (Human Genome U133 Plus 2.0 Array)   214794_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447389
Ensembl peptide - ENSP00000448557
Ensembl peptide - ENSP00000447615
Ensembl peptide - ENSP00000302886
NCBI entrez gene - 5036     See in Manteia.
OMIM - 602145
RefSeq - NM_006191
RefSeq Peptide - NP_006182
swissprot - F8W0A3
swissprot - A0A024RB85
swissprot - Q9UQ80
swissprot - F8VR77
swissprot - F8VZ69
Ensembl - ENSG00000170515
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pa2g4aENSDARG00000039578Danio rerio
 pa2g4bENSDARG00000070657Danio rerio
 ENSGALG00000034218Gallus gallus
 Pa2g4ENSMUSG00000025364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC034102.2ENSG0000025741137
METAP2 / P50579 / methionyl aminopeptidase 2ENSG0000011114219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000994  Peptidase M24
 IPR004545  PA2G4 family
 IPR018349  Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site
 IPR036005  Creatinase/aminopeptidase-like
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045597 positive regulation of cell differentiation ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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