ENSG00000171497


Homo sapiens

Features
Gene ID: ENSG00000171497
  
Biological name :PPID
  
Synonyms : peptidylprolyl isomerase D / PPID / Q08752
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.1
Gene start: 158709134
Gene end: 158723396
  
Corresponding Affymetrix probe sets: 204185_x_at (Human Genome U133 Plus 2.0 Array)   204186_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303754
Ensembl peptide - ENSP00000423207
Ensembl peptide - ENSP00000421221
NCBI entrez gene - 5481     See in Manteia.
OMIM - 601753
RefSeq - NM_005038
RefSeq Peptide - NP_005029
swissprot - Q08752
swissprot - H0Y969
swissprot - H0Y8J0
swissprot - E5KN55
Ensembl - ENSG00000171497
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppidENSDARG00000038835Danio rerio
 PPIDENSGALG00000009451Gallus gallus
 PpidENSMUSG00000027804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKTR / P30414 / natural killer cell triggering receptorENSG0000011485736
PPIG / Q13427 / peptidylprolyl isomerase GENSG0000013839836


Protein motifs (from Interpro)
Interpro ID Name
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR024936  Cyclophilin-type peptidyl-prolyl cis-trans isomerase
 IPR029000  Cyclophilin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006457 protein folding ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019076 viral release from host cell TAS
 biological_processGO:0034389 lipid particle organization IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0050714 positive regulation of protein secretion IMP
 biological_processGO:0061077 chaperone-mediated protein folding IDA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0071492 cellular response to UV-A IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008134 transcription factor binding IDA
 molecular_functionGO:0016018 cyclosporin A binding TAS
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0030331 estrogen receptor binding ISS
 molecular_functionGO:0030544 Hsp70 protein binding ISS
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0051879 Hsp90 protein binding IDA


Pathways (from Reactome)
Pathway description
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000091831 ESR1 / P03372 / estrogen receptor 1  / complex
 ENSG00000110958 PTGES3 / Q15185 / prostaglandin E synthase 3  / complex
 ENSG00000140009 ESR2 / Q92731 / estrogen receptor 2  / complex
 ENSG00000080824 P07900 / HSP90AA1 / heat shock protein 90 alpha family class A member 1  / complex
 ENSG00000171497 PPID / Q08752 / peptidylprolyl isomerase D  / complex
 ENSG00000096384 P08238 / HSP90AB1 / heat shock protein 90 alpha family class B member 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr