ENSG00000173110


Homo sapiens

Features
Gene ID: ENSG00000173110
  
Biological name :HSPA6
  
Synonyms : heat shock protein family A (Hsp70) member 6 / HSPA6 / P17066
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.3
Gene start: 161524540
Gene end: 161526910
  
Corresponding Affymetrix probe sets: 117_at (Human Genome U133 Plus 2.0 Array)   213418_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310219
NCBI entrez gene - 3310     See in Manteia.
OMIM - 140555
RefSeq - NM_002155
RefSeq Peptide - NP_002146
swissprot - P17066
Ensembl - ENSG00000173110
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA1A / P0DMV8 / heat shock protein family A (Hsp70) member 1AENSG0000020438981
HSPA1B / P0DMV9 / heat shock protein family A (Hsp70) member 1BENSG0000020438881
HSPA1L / P34931 / heat shock protein family A (Hsp70) member 1 likeENSG0000020439079
HSPA8 / P11142 / heat shock protein family A (Hsp70) member 8ENSG0000010997178
HSPA2 / P54652 / heat shock protein family A (Hsp70) member 2ENSG0000012680378
HSPA5 / P11021 / heat shock protein family A (Hsp70) member 5ENSG0000004457461
HSPA14 / Q0VDF9 / heat shock protein family A (Hsp70) member 14ENSG0000018752228
HSPA14 / heat shock protein family A (Hsp70) member 14ENSG000002840247


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006986 response to unfolded protein TAS
 biological_processGO:0034605 cellular response to heat IMP
 biological_processGO:0042026 protein refolding IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0042623 ATPase activity, coupled IDA
 molecular_functionGO:0051082 unfolded protein binding IDA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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