ENSG00000178982


Homo sapiens

Features
Gene ID: ENSG00000178982
  
Biological name :EIF3K
  
Synonyms : EIF3K / eukaryotic translation initiation factor 3 subunit K / Q9UBQ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 38619082
Gene end: 38636955
  
Corresponding Affymetrix probe sets: 210501_x_at (Human Genome U133 Plus 2.0 Array)   212716_s_at (Human Genome U133 Plus 2.0 Array)   221071_at (Human Genome U133 Plus 2.0 Array)   221494_x_at (Human Genome U133 Plus 2.0 Array)   236605_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467895
Ensembl peptide - ENSP00000479334
Ensembl peptide - ENSP00000468525
Ensembl peptide - ENSP00000468231
Ensembl peptide - ENSP00000248342
Ensembl peptide - ENSP00000438145
Ensembl peptide - ENSP00000440999
Ensembl peptide - ENSP00000465460
NCBI entrez gene - 27335     See in Manteia.
OMIM - 609596
RefSeq - NM_001308393
RefSeq - NM_013234
RefSeq - NM_001300992
RefSeq Peptide - NP_001287921
RefSeq Peptide - NP_001295322
RefSeq Peptide - NP_037366
swissprot - Q9UBQ5
swissprot - A0A087WVB9
swissprot - K7EK53
swissprot - K7EQM4
swissprot - K7ERF1
swissprot - K7ES31
swissprot - B4DQ48
Ensembl - ENSG00000178982
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3kENSDARG00000068289Danio rerio
 TGM2ENSGALG00000029343Gallus gallus
 Eif3kENSMUSG00000053565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009374  Eukaryotic translation initiation factor 3 subunit K
 IPR016020  Translation initiation factor 3, subunit 12, N-terminal, eukaryotic
 IPR016024  Armadillo-type fold
 IPR033464  CSN8/PSMD8/EIF3K
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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