ENSG00000182934


Homo sapiens

Features
Gene ID: ENSG00000182934
  
Biological name :SRPRA
  
Synonyms : P08240 / SRPRA / SRP receptor alpha subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q24.2
Gene start: 126262919
Gene end: 126269144
  
Corresponding Affymetrix probe sets: 200917_s_at (Human Genome U133 Plus 2.0 Array)   200918_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328023
Ensembl peptide - ENSP00000435508
NCBI entrez gene - 6734     See in Manteia.
OMIM - 182180
RefSeq - XM_017018179
RefSeq - NM_001177842
RefSeq - NM_003139
RefSeq Peptide - NP_003130
RefSeq Peptide - NP_001171313
swissprot - P08240
Ensembl - ENSG00000182934
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srprENSDARG00000061124Danio rerio
 SRPRAENSGALG00000030759Gallus gallus
 SrprENSMUSG00000032042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000897  Signal recognition particle, SRP54 subunit, GTPase domain
 IPR003593  AAA+ ATPase domain
 IPR007222  Signal recognition particle receptor, alpha subunit, N-terminal
 IPR011012  Longin-like domain superfamily
 IPR013822  Signal recognition particle, SRP54 subunit, helical bundle
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036225  SRP/SRP receptor, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006613 cotranslational protein targeting to membrane TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005785 signal recognition particle receptor complex TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005047 signal recognition particle binding TAS
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000144867 SRPRB / Q9Y5M8 / SRP receptor beta subunit  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr