ENSG00000185009


Homo sapiens

Features
Gene ID: ENSG00000185009
  
Biological name :AP3M1
  
Synonyms : adaptor related protein complex 3 mu 1 subunit / AP3M1 / Q9Y2T2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q22.2
Gene start: 74120255
Gene end: 74151063
  
Corresponding Affymetrix probe sets: 222516_at (Human Genome U133 Plus 2.0 Array)   222517_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361831
Ensembl peptide - ENSP00000347408
NCBI entrez gene - 26985     See in Manteia.
OMIM - 610366
RefSeq - NM_012095
RefSeq - NM_001320263
RefSeq - NM_001320264
RefSeq - NM_001320265
RefSeq - NM_207012
RefSeq Peptide - NP_001307194
RefSeq Peptide - NP_001307192
RefSeq Peptide - NP_001307193
RefSeq Peptide - NP_036227
RefSeq Peptide - NP_996895
swissprot - Q9Y2T2
swissprot - A0A024QZR5
Ensembl - ENSG00000185009
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ap3m1ENSDARG00000029928Danio rerio
 AP3M1ENSGALG00000005070Gallus gallus
 Ap3m1ENSMUSG00000021824Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AP3M2 / P53677 / adaptor related protein complex 3 mu 2 subunitENSG0000007071884
AP1M2 / Q9Y6Q5 / adaptor related protein complex 1 mu 2 subunitENSG0000012935429
AP1M1 / Q9BXS5 / adaptor related protein complex 1 mu 1 subunitENSG0000007295828
AP2M1 / Q96CW1 / adaptor related protein complex 2 mu 1 subunitENSG0000016120326
AP4M1 / O00189 / adaptor related protein complex 4 mu 1 subunitENSG0000022183824


Protein motifs (from Interpro)
Interpro ID Name
 IPR001392  Clathrin adaptor, mu subunit
 IPR011012  Longin-like domain superfamily
 IPR018240  Clathrin adaptor, mu subunit, conserved site
 IPR022775  AP complex, mu/sigma subunit
 IPR028565  Mu homology domain
 IPR036168  AP-2 complex subunit mu, C-terminal superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006622 protein targeting to lysosome TAS
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0008089 anterograde axonal transport ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048490 anterograde synaptic vesicle transport ISS
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030131 clathrin adaptor complex IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IPI


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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