ENSG00000198901


Homo sapiens

Features
Gene ID: ENSG00000198901
  
Biological name :PRC1
  
Synonyms : O43663 / PRC1 / protein regulator of cytokinesis 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q26.1
Gene start: 90966038
Gene end: 90995629
  
Corresponding Affymetrix probe sets: 218009_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456737
Ensembl peptide - ENSP00000453455
Ensembl peptide - ENSP00000453977
Ensembl peptide - ENSP00000354679
Ensembl peptide - ENSP00000377793
Ensembl peptide - ENSP00000409549
Ensembl peptide - ENSP00000451344
Ensembl peptide - ENSP00000453063
Ensembl peptide - ENSP00000453117
NCBI entrez gene - 9055     See in Manteia.
OMIM - 603484
RefSeq - XM_017022717
RefSeq - XM_011522188
RefSeq - XM_011522189
RefSeq - XM_011522190
RefSeq - XM_011522191
RefSeq - XM_011522192
RefSeq - XM_017022712
RefSeq - XM_017022713
RefSeq - XM_017022714
RefSeq - XM_017022715
RefSeq - XM_017022716
RefSeq - NM_001267580
RefSeq - NM_003981
RefSeq - NM_199413
RefSeq - XM_005254987
RefSeq - XM_006720759
RefSeq - XM_006720760
RefSeq - XM_011522187
RefSeq Peptide - NP_003972
RefSeq Peptide - NP_955445
RefSeq Peptide - NP_001254509
swissprot - H0YNE4
swissprot - H3BSJ8
swissprot - H0YL53
swissprot - O43663
swissprot - G3V3N7
swissprot - H0YLA0
swissprot - H0YM42
Ensembl - ENSG00000198901
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prc1aENSDARG00000100918Danio rerio
 prc1bENSDARG00000005993Danio rerio
 ENSGALG00000043144Gallus gallus
 PRC1ENSGALG00000012836Gallus gallus
 Prc1ENSMUSG00000038943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007145  Microtubule-associated protein, MAP65/Ase1/PRC1
 IPR032921  Protein regulator of cytokinesis 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000022 mitotic spindle elongation TAS
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0032465 regulation of cytokinesis IDA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule TAS
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0070938 contractile ring IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019894 kinesin binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
RHO GTPases activate CIT


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118193 KIF14 / Q15058 / kinesin family member 14  / complex / reaction
 ENSG00000143878 RHOB / P62745 / ras homolog family member B  / reaction / complex
 ENSG00000155366 RHOC / P08134 / ras homolog family member C  / reaction / complex
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / complex / reaction
 ENSG00000122966 CIT / O14578 / citron rho-interacting serine/threonine kinase  / reaction / complex
 ENSG00000136238 RAC1 / P63000 / Rac family small GTPase 1  / complex / reaction






 

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