ENSG00000204435


Homo sapiens

Features
Gene ID: ENSG00000204435
  
Biological name :CSNK2B
  
Synonyms : casein kinase 2 beta / CSNK2B / P67870
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.33
Gene start: 31665236
Gene end: 31670343
  
Corresponding Affymetrix probe sets: 201390_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365025
Ensembl peptide - ENSP00000365026
Ensembl peptide - ENSP00000365042
Ensembl peptide - ENSP00000365046
NCBI entrez gene - 1460     See in Manteia.
OMIM - 115441
RefSeq - NM_001282385
RefSeq - NM_001320
RefSeq Peptide - NP_001269314
RefSeq Peptide - NP_001311
swissprot - Q5SRQ6
swissprot - N0E4C7
swissprot - P67870
Ensembl - ENSG00000204435
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csnk2bENSDARG00000077776Danio rerio
 Csnk2bENSMUSG00000024387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000704  Casein kinase II, regulatory subunit
 IPR016149  Casein kinase II, regulatory subunit, N-terminal
 IPR035991  Casein kinase II subunit beta-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0006656 phosphatidylcholine biosynthetic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0032927 positive regulation of activin receptor signaling pathway IMP
 biological_processGO:0033211 adiponectin-activated signaling pathway IDA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0034622 cellular protein-containing complex assembly NAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:0051101 regulation of DNA binding NAS
 biological_processGO:0061154 endothelial tube morphogenesis IMP
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005956 protein kinase CK2 complex IDA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0031519 PcG protein complex IDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0019887 protein kinase regulator activity NAS
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC
WNT mediated activation of DVL
Condensation of Prometaphase Chromosomes
Signal transduction by L1
Neutrophil degranulation
Regulation of TP53 Activity through Phosphorylation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Receptor Mediated Mitophagy
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000092201 Q9Y5B9 / SUPT16H / SPT16 homolog, facilitates chromatin remodeling subunit  / complex / reaction
 ENSG00000101266 P68400 / CSNK2A1 / casein kinase 2 alpha 1  / complex
 ENSG00000070770 P19784 / CSNK2A2 / casein kinase 2 alpha 2  / complex
 ENSG00000149136 SSRP1 / Q08945 / structure specific recognition protein 1  / complex / reaction
 ENSG00000198910 L1CAM / P32004 / L1 cell adhesion molecule  / complex / reaction
 ENSG00000136940 PDCL / Q13371 / phosducin like  / reaction
 ENSG00000069509 FUNDC1 / Q8IVP5 / FUN14 domain containing 1  / reaction
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / reaction
 ENSG00000171862 PTEN / P60484 / phosphatase and tensin homolog  / reaction
 ENSG00000107404 DVL1 / O14640 / dishevelled segment polarity protein 1  / reaction
 ENSG00000161202 DVL3 / Q92997 / dishevelled segment polarity protein 3  / reaction
 ENSG00000204435 CSNK2B / P67870 / casein kinase 2 beta  / complex
 ENSG00000004975 DVL2 / O14641 / dishevelled segment polarity protein 2  / reaction
 ENSG00000214530 Q9Y365 / STARD10 / StAR related lipid transfer domain containing 10  / reaction






 

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