MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0000937 | abnormal motor neuron morphology | "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0000951 | sporadic seizures | "occasional seizures occuring at irregular intervals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001177 | atelectasis | "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001504 | abnormal posture | "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0001951 | abnormal breathing | "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0002064 | seizures | "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0004008 | abnormal GABA receptor currents | "change in the measured amplitude or duration of response to stimulation of GABA receptors" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0004768 | abnormal axonal transport | "any functional anomaly of the directed movement of organelles or vesicles along microtubules in nerve cell axons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0005405 | axon degeneration | "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0008469 | abnormal protein level | "anomaly in the amount of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0008546 | abnormal vesicle-mediated transport | "anomaly in the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell" [GO:0016192] |
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Allelic Composition: Foxo3mommeR1/Foxo3tm1.1Rdp,Tg(HBA1-Gfp)1Ew/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ
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MP:0009435 | abnormal miniature inhibitory postsynaptic currents | "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0011084 | partial lethality at weaning | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Gli3Pdn/Gli3+ Genetic Background: involves: Jcl:ICR
Allelic Composition: Kif5atm1.1Noh/Kif5atm1.1Noh Genetic Background: B6.129S6-Kif5atm1.1Noh
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