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Manteia - Lookalike Myopathies


 

ARCHIVE v.4

 

Prioritize candidate genes.

    This tool allows to search for genes with similar annotations with a training set. This can be used to prioritize candidate genes having similar properties with a set of disease genes.

* Enter the Ensembl IDs corresponding to the training set of genes in the "training genes" box.

* For advanced users: alternatively, you can enter your own selection of annotation keywords with their type ( among "Phenotype", "Gene Ontology BP", "Gene Ontology MF", "Gene Ontology CC", "Protein motif" or "Chromosome distribution") and Pvalues in a tabulated format in the "Pvalue mode" panel.

* Enter the Ensembl IDs corresponding to the candidate genes in the "candidate genes" box.

* Select the type of annotation you want to include in the analysis.

* Press "Submit".


Note: if you don't have Ensembl IDs, use "Batch Gene Entry" to convert your identifiers then use "Export gene ID list" in the "Refine" menu.

If no candidate genes are provided, the entire genome will be analyzed.







     E.g. Myopathies:
 
Lookalike
 
Training gene ID list*:


Candidate gene ID list*:


Orthology
Do not use Orthology.
Convert training and candidate gene sets to mouse orthologs.
Convert human gene annotation to prioritize mouse genes.
Use phenotype from mouse orthologs.

Annotation sets to include in the search
Gene Ontology Biological Process Gene Ontology Molecular function Gene Ontology Cellular component
Phenotype annotation
Protein motifs
Chromosomal locus distribution
Paralogs
Interactome
co-occurrence in PubMed articles




   
 Enter your IDs one per line, separated by a space or a ":"



 

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The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2017
contact: otassy@igbmc.fr