1017


Homo sapiens (NCBI)

Features
Gene ID: 1017
  
Biological name :
  
Synonyms : CDK2 / CDKN2|p33(CDK2) / cyclin dependent kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204252_at (Human Genome U133 Plus 2.0 Array)   211803_at (Human Genome U133 Plus 2.0 Array)   211804_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 166362719
RefSeq - 16936528
RefSeq - 589811557
RefSeq - 767972772
RefSeq - NC_000012.12
RefSeq - NG_034014.1
RefSeq - NP_001277159.1
RefSeq - NP_001789.2
RefSeq - NP_439892.2
RefSeq - XP_011536034.1
RefSeq - NM_001290230.1
RefSeq - NM_001798.4
RefSeq - NM_052827.3
RefSeq - XM_011537732.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000123374 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007099 centriole replication IMP
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007265 Ras protein signal transduction IEP
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010033 response to organic substance IBA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle IBA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016572 histone phosphorylation IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0031571 mitotic G1 DNA damage checkpoint TAS
 biological_processGO:0032298 positive regulation of DNA-dependent DNA replication initiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051298 centrosome duplication TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle TAS
 biological_processGO:0060968 regulation of gene silencing IDA
 biological_processGO:0071732 cellular response to nitric oxide TAS
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IDA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000793 condensed chromosome IEA
 cellular_componentGO:0000805 X chromosome IEA
 cellular_componentGO:0000806 Y chromosome IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005813 centrosome TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0015030 Cajal body IDA
 cellular_componentGO:0097123 cyclin A1-CDK2 complex IEA
 cellular_componentGO:0097124 cyclin A2-CDK2 complex IDA
 cellular_componentGO:0097134 cyclin E1-CDK2 complex IEA
 cellular_componentGO:0097135 cyclin E2-CDK2 complex IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IGI
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0035173 histone kinase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0097472 cyclin-dependent protein kinase activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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