1019


Homo sapiens (NCBI)

Features
Gene ID: 1019
  
Biological name :
  
Synonyms : CDK4 / CMM3|PSK-J3 / cyclin dependent kinase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202246_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4502735
RefSeq - NC_000012.12
RefSeq - NG_007484.2
RefSeq - NP_000066.1
RefSeq - NM_000075.3
RefSeq - NM_052984.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000135446 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IMP
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0010288 response to lead ion IEA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IDA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0031658 negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle TAS
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0042493 response to drug IEP
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045787 positive regulation of cell cycle TAS
 biological_processGO:0045793 positive regulation of cell size IEA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046890 regulation of lipid biosynthetic process IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IMP
 biological_processGO:0050994 regulation of lipid catabolic process IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0055093 response to hyperoxia IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:1904628 cellular response to phorbol 13-acetate 12-myristate IEA
 biological_processGO:1904637 cellular response to ionomycin IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IDA
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097129 cyclin D2-CDK4 complex IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity TAS
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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