10395


Homo sapiens (NCBI)
regulationactivitysignaltransductioncellactincytoskeletonproteingtpasefocaladhesionassemblybindingmorphogenesisapoptoticprocessorganizationneuraltubeclosureheartactivationcysteine-typeendopeptidaseinvolvedproliferationshapehindbrainmigrationforebrain

Features
Gene ID: 10395
  
Biological name :
  
Synonyms : ARHGAP7|HP|STARD12|p122-RhoGAP / DLC1 / DLC1 Rho GTPase activating protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210762_s_at (Human Genome U133 Plus 2.0 Array)   220511_s_at (Human Genome U133 Plus 2.0 Array)   220512_at (Human Genome U133 Plus 2.0 Array)   224822_at (Human Genome U133 Plus 2.0 Array)   242631_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1128611433
RefSeq - 1128611439
RefSeq - 1128611462
RefSeq - 1128611467
RefSeq - 256017148
RefSeq - 256017150
RefSeq - 256017153
RefSeq - 33188437
RefSeq - 530387511
RefSeq - 939699139
RefSeq - NC_000008.11
RefSeq - NG_015998.2
RefSeq - NP_001303597.1
RefSeq - NP_001335010.1
RefSeq - NP_001335011.1
RefSeq - NP_001335012.1
RefSeq - NP_001335013.1
RefSeq - NP_006085.2
RefSeq - NP_079043.3
RefSeq - NP_872584.2
RefSeq - NW_018654717.1
RefSeq - XP_005273431.1
RefSeq - NP_001157743.1
RefSeq - NM_001164271.1
RefSeq - NM_001316668.1
RefSeq - NM_001348081.1
RefSeq - NM_001348082.1
RefSeq - NM_001348083.1
RefSeq - NM_001348084.1
RefSeq - NM_006094.4
RefSeq - NM_024767.3
RefSeq - NM_182643.2
RefSeq - XM_005273374.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164741 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomical structure developmentcell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationregulation of biological qualitycellular developmental processactin filament-based processlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscell adhesionanatomicanatomical structure developmentcell deacell deathnitrogennitrogen compound metabolic processcellularcellular metabolic processprimary primary metabolic processregulatiregulation of molecular functionorganic organic substance metabolic processcell comcell communicationcellularcellular response to stimuluscellularcellular component organizationregulatiregulation of biological qualitycellularcellular developmental processactin fiactin filament-based processlocalizalocalization of cellmovementmovement of cell or subcellular componentcellularcellular component biogenesiscell adhcell adhesion
enzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityprotein bindinglipid bindingenzyme regulator activityenzyme regulator activityprotein bindingprotein bindinglipid bindinglipid binding
cellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellorganellemembranecell junctioncellcellorganelleorganellemembranemembranecell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure ISS
 biological_processGO:0003007 heart morphogenesis ISS
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0021575 hindbrain morphogenesis ISS
 biological_processGO:0030036 actin cytoskeleton organization ISS
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0030900 forebrain development ISS
 biological_processGO:0032956 regulation of actin cytoskeleton organization IMP
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IMP
 biological_processGO:0035307 positive regulation of protein dephosphorylation IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048041 focal adhesion assembly ISS
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 biological_processGO:0051895 negative regulation of focal adhesion assembly IDA
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042169 SH2 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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