10891


Homo sapiens (NCBI)

Features
Gene ID: 10891
  
Biological name :
  
Synonyms : LEM6|PGC-1(alpha)|PGC-1alpha|PGC-1v|PGC1|PGC1A|PPARGC1 / PPARGC1A / PPARG coactivator 1 alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1569141_a_at (Human Genome U133 Plus 2.0 Array)   219195_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767929616
RefSeq - 1064788217
RefSeq - 1064788219
RefSeq - 1236589313
RefSeq - 1236589319
RefSeq - 1237937874
RefSeq - 1237938322
RefSeq - 1370486115
RefSeq - 530376245
RefSeq - 530376247
RefSeq - 530376251
RefSeq - 7019499
RefSeq - 767929609
RefSeq - 767929613
RefSeq - 1064788214
RefSeq - 767929620
RefSeq - NC_000004.12
RefSeq - NG_028250.2
RefSeq - NP_001317680.1
RefSeq - NP_001317681.1
RefSeq - NP_001317682.1
RefSeq - NP_001341754.1
RefSeq - NP_001341755.1
RefSeq - NP_001341756.1
RefSeq - NP_001341757.1
RefSeq - NP_037393.1
RefSeq - XP_005248188.1
RefSeq - XP_005248189.1
RefSeq - XP_005248191.1
RefSeq - XP_011512068.1
RefSeq - XP_011512070.1
RefSeq - XP_011512071.1
RefSeq - XP_011512073.1
RefSeq - XP_024309646.1
RefSeq - NR_148981.1
RefSeq - NR_148982.1
RefSeq - NR_148983.1
RefSeq - NR_148984.1
RefSeq - NR_148985.1
RefSeq - NR_148986.1
RefSeq - NR_148987.1
RefSeq - NM_001330751.1
RefSeq - NM_001330752.1
RefSeq - NM_001330753.1
RefSeq - NM_001354825.1
RefSeq - NM_001354826.1
RefSeq - NM_001354827.1
RefSeq - NM_001354828.1
RefSeq - NM_013261.4
RefSeq - XM_005248131.5
RefSeq - XM_005248132.1
RefSeq - XM_005248134.4
RefSeq - XM_011513766.1
RefSeq - XM_011513768.1
RefSeq - XM_011513769.2
RefSeq - XM_011513771.1
RefSeq - XM_024453878.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000109819 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000302 response to reactive oxygen species IEA
 biological_processGO:0000422 autophagy of mitochondrion IEA
 biological_processGO:0001659 temperature homeostasis TAS
 biological_processGO:0001678 cellular glucose homeostasis NAS
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0002021 response to dietary excess IEA
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0006012 galactose metabolic process IEA
 biological_processGO:0006094 gluconeogenesis NAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0007005 mitochondrion organization TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0007586 digestion TAS
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0008209 androgen metabolic process IEA
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0010822 positive regulation of mitochondrion organization ISS
 biological_processGO:0014732 skeletal muscle atrophy IEA
 biological_processGO:0014850 response to muscle activity ISS
 biological_processGO:0014878 response to electrical stimulus involved in regulation of muscle adaptation IEA
 biological_processGO:0014912 negative regulation of smooth muscle cell migration IEA
 biological_processGO:0019395 fatty acid oxidation NAS
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0022904 respiratory electron transport chain ISS
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0032922 circadian regulation of gene expression ISS
 biological_processGO:0034599 cellular response to oxidative stress ISS
 biological_processGO:0035066 positive regulation of histone acetylation TAS
 biological_processGO:0035865 cellular response to potassium ion IEA
 biological_processGO:0042594 response to starvation NAS
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0043201 response to leucine IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0045333 cellular respiration TAS
 biological_processGO:0045722 positive regulation of gluconeogenesis TAS
 biological_processGO:0045820 negative regulation of glycolytic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046321 positive regulation of fatty acid oxidation TAS
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050821 protein stabilization TAS
 biological_processGO:0050873 brown fat cell differentiation TAS
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051552 flavone metabolic process IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071250 cellular response to nitrite IEA
 biological_processGO:0071313 cellular response to caffeine IEA
 biological_processGO:0071332 cellular response to fructose stimulus IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071354 cellular response to interleukin-6 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071372 cellular response to follicle-stimulating hormone stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0071871 response to epinephrine IEA
 biological_processGO:0071873 response to norepinephrine IEA
 biological_processGO:0090258 negative regulation of mitochondrial fission IEA
 biological_processGO:0097009 energy homeostasis ISS
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 biological_processGO:1901215 negative regulation of neuron death IGI
 biological_processGO:1901558 response to metformin IEA
 biological_processGO:1901857 positive regulation of cellular respiration IEA
 biological_processGO:1901860 positive regulation of mitochondrial DNA metabolic process IEA
 biological_processGO:1901863 positive regulation of muscle tissue development IEA
 biological_processGO:1904635 positive regulation of glomerular visceral epithelial cell apoptotic process IEA
 biological_processGO:1904637 cellular response to ionomycin IEA
 biological_processGO:1904639 cellular response to resveratrol IEA
 biological_processGO:1904640 response to methionine IEA
 biological_processGO:1990845 adaptive thermogenesis IEA
 biological_processGO:2000184 positive regulation of progesterone biosynthetic process IEA
 biological_processGO:2000272 negative regulation of signaling receptor activity IEA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 biological_processGO:2001171 positive regulation of ATP biosynthetic process ISS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex TAS
 cellular_componentGO:0005719 nuclear euchromatin IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0022626 cytosolic ribosome IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0097440 apical dendrite IEA
 cellular_componentGO:1990843 subsarcolemmal mitochondrion IEA
 cellular_componentGO:1990844 interfibrillar mitochondrion IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003712 transcription coregulator activity TAS
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding TAS
 molecular_functionGO:0016922 nuclear receptor binding IPI
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IDA
 molecular_functionGO:0031490 chromatin DNA binding ISS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA
 molecular_functionGO:0043014 alpha-tubulin binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0050681 androgen receptor binding NAS
 molecular_functionGO:1990841 promoter-specific chromatin binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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