11200


Homo sapiens (NCBI)

Features
Gene ID: 11200
  
Biological name :
  
Synonyms : CDS1|CHK2|HuCds1|LFS2|PP1425|RAD53|hCds1 / checkpoint kinase 2 / CHEK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210416_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 768023221
RefSeq - 1034628175
RefSeq - 1034628181
RefSeq - 1171342935
RefSeq - 1370481812
RefSeq - 1370481814
RefSeq - 22209009
RefSeq - 383792178
RefSeq - 54112407
RefSeq - 6005850
RefSeq - 768023201
RefSeq - 768023205
RefSeq - 768023209
RefSeq - 768023213
RefSeq - 1034628170
RefSeq - 768023226
RefSeq - 768023234
RefSeq - NC_000022.11
RefSeq - NG_008150.2
RefSeq - NP_001005735.1
RefSeq - NP_001244316.1
RefSeq - NP_001336885.1
RefSeq - NP_009125.1
RefSeq - NP_665861.1
RefSeq - XP_006724177.2
RefSeq - XP_006724179.2
RefSeq - XP_011528141.1
RefSeq - XP_011528142.1
RefSeq - XP_011528143.1
RefSeq - XP_011528144.1
RefSeq - XP_011528146.1
RefSeq - XP_011528147.1
RefSeq - XP_016884049.1
RefSeq - XP_016884050.1
RefSeq - XP_024307916.1
RefSeq - XP_024307917.1
RefSeq - XM_011529845.2
RefSeq - XM_017028560.1
RefSeq - XM_017028561.2
RefSeq - NM_001005735.1
RefSeq - NM_001257387.1
RefSeq - NM_001349956.1
RefSeq - NM_007194.3
RefSeq - NM_145862.2
RefSeq - XM_024452148.1
RefSeq - XM_024452149.1
RefSeq - XR_937805.2
RefSeq - XR_937806.2
RefSeq - XR_937807.2
RefSeq - XM_006724114.3
RefSeq - XM_006724116.2
RefSeq - XM_011529839.2
RefSeq - XM_011529840.3
RefSeq - XM_011529841.1
RefSeq - XM_011529842.2
RefSeq - XM_011529844.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000183765 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint TAS
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IMP
 biological_processGO:0001302 replicative cell aging IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus TAS
 biological_processGO:0006975 DNA damage induced protein phosphorylation IMP
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0042176 regulation of protein catabolic process IMP
 biological_processGO:0042770 signal transduction in response to DNA damage IDA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0044257 cellular protein catabolic process IMP
 biological_processGO:0044773 mitotic DNA damage checkpoint IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0072428 signal transduction involved in intra-S DNA damage checkpoint IMP
 biological_processGO:0090307 mitotic spindle assembly IMP
 biological_processGO:0090399 replicative senescence NAS
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1903416 response to glycoside IEA
 biological_processGO:1903926 cellular response to bisphenol A IEA
 biological_processGO:2000002 negative regulation of DNA damage checkpoint IEA
 biological_processGO:2000210 positive regulation of anoikis IEA
 cellular_componentGO:0000781 chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016605 PML body IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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