11315


Homo sapiens (NCBI)

Features
Gene ID: 11315
  
Biological name :
  
Synonyms : DJ-1|DJ1|GATD2|HEL-S-67p / PARK7 / Parkinsonism associated deglycase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 200006_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 183227678
RefSeq - 31543380
RefSeq - 530360487
RefSeq - NC_000001.11
RefSeq - NG_008271.1
RefSeq - NP_001116849.1
RefSeq - NP_009193.2
RefSeq - XP_005263481.1
RefSeq - NM_001123377.1
RefSeq - NM_007262.4
RefSeq - XM_005263424.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000116288 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IGI
 biological_processGO:0002866 positive regulation of acute inflammatory response to antigenic stimulus ISS
 biological_processGO:0006281 DNA repair IDA
 biological_processGO:0006469 negative regulation of protein kinase activity IGI
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006517 protein deglycosylation IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007005 mitochondrion organization ISS
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0009438 methylglyoxal metabolic process IDA
 biological_processGO:0010273 detoxification of copper ion IMP
 biological_processGO:0010628 positive regulation of gene expression TAS
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0018323 enzyme active site formation via L-cysteine sulfinic acid IEA
 biological_processGO:0019249 lactate biosynthetic process IDA
 biological_processGO:0030073 insulin secretion ISS
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0032091 negative regulation of protein binding IMP
 biological_processGO:0032148 activation of protein kinase B activity IC
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0033234 negative regulation of protein sumoylation IDA
 biological_processGO:0033864 positive regulation of NAD(P)H oxidase activity ISS
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0036471 cellular response to glyoxal IDA
 biological_processGO:0036526 peptidyl-cysteine deglycation IDA
 biological_processGO:0036527 peptidyl-arginine deglycation IDA
 biological_processGO:0036528 peptidyl-lysine deglycation IDA
 biological_processGO:0036529 protein deglycation, glyoxal removal IDA
 biological_processGO:0036530 protein deglycation, methylglyoxal removal IDA
 biological_processGO:0036531 glutathione deglycation IDA
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0042743 hydrogen peroxide metabolic process IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043523 regulation of neuron apoptotic process IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0045560 regulation of TRAIL receptor biosynthetic process IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046295 glycolate biosynthetic process IDA
 biological_processGO:0046826 negative regulation of protein export from nucleus IGI
 biological_processGO:0050727 regulation of inflammatory response ISS
 biological_processGO:0050787 detoxification of mercury ion IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity TAS
 biological_processGO:0051444 negative regulation of ubiquitin-protein transferase activity IDA
 biological_processGO:0051583 dopamine uptake involved in synaptic transmission IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling IC
 biological_processGO:0051899 membrane depolarization IEA
 biological_processGO:0060081 membrane hyperpolarization IEA
 biological_processGO:0060548 negative regulation of cell death IDA
 biological_processGO:0060765 regulation of androgen receptor signaling pathway IDA
 biological_processGO:0070301 cellular response to hydrogen peroxide IDA
 biological_processGO:0090073 positive regulation of protein homodimerization activity IDA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:0106044 guanine deglycation IDA
 biological_processGO:0106045 guanine deglycation, methylglyoxal removal IDA
 biological_processGO:0106046 guanine deglycation, glyoxal removal IDA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IMP
 biological_processGO:1901215 negative regulation of neuron death IDA
 biological_processGO:1901671 positive regulation of superoxide dismutase activity IDA
 biological_processGO:1901984 negative regulation of protein acetylation IDA
 biological_processGO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
 biological_processGO:1902903 regulation of supramolecular fiber organization TAS
 biological_processGO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone IMP
 biological_processGO:1903073 negative regulation of death-inducing signaling complex assembly IC
 biological_processGO:1903094 negative regulation of protein K48-linked deubiquitination IDA
 biological_processGO:1903122 negative regulation of TRAIL-activated apoptotic signaling pathway IMP
 biological_processGO:1903168 positive regulation of pyrroline-5-carboxylate reductase activity IDA
 biological_processGO:1903178 positive regulation of tyrosine 3-monooxygenase activity IDA
 biological_processGO:1903181 positive regulation of dopamine biosynthetic process IDA
 biological_processGO:1903189 glyoxal metabolic process IDA
 biological_processGO:1903197 positive regulation of L-dopa biosynthetic process IMP
 biological_processGO:1903200 positive regulation of L-dopa decarboxylase activity IDA
 biological_processGO:1903202 negative regulation of oxidative stress-induced cell death IDA
 biological_processGO:1903206 negative regulation of hydrogen peroxide-induced cell death IMP
 biological_processGO:1903208 negative regulation of hydrogen peroxide-induced neuron death IDA
 biological_processGO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IDA
 biological_processGO:1903384 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway IGI
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process ISS
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process IEA
 biological_processGO:1903599 positive regulation of autophagy of mitochondrion NAS
 biological_processGO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:2000157 negative regulation of ubiquitin-specific protease activity IDA
 biological_processGO:2000277 positive regulation of oxidative phosphorylation uncoupler activity IEA
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IMP
 biological_processGO:2000825 positive regulation of androgen receptor activity IMP
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IMP
 biological_processGO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IMP
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IDA
 cellular_componentGO:0005758 mitochondrial intermembrane space IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005913 cell-cell adherens junction HDA
 cellular_componentGO:0016605 PML body IDA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0001047 core promoter binding IC
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005507 copper ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0016532 superoxide dismutase copper chaperone activity IDA
 molecular_functionGO:0016684 oxidoreductase activity, acting on peroxide as acceptor IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0019955 cytokine binding IPI
 molecular_functionGO:0036470 tyrosine 3-monooxygenase activator activity IDA
 molecular_functionGO:0036478 L-dopa decarboxylase activator activity IDA
 molecular_functionGO:0036524 protein deglycase activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044388 small protein activating enzyme binding IPI
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0045340 mercury ion binding IDA
 molecular_functionGO:0050681 androgen receptor binding IPI
 molecular_functionGO:0051920 peroxiredoxin activity IEA
 molecular_functionGO:0070491 repressing transcription factor binding IPI
 molecular_functionGO:0097110 scaffold protein binding IPI
 molecular_functionGO:1903135 cupric ion binding IDA
 molecular_functionGO:1903136 cuprous ion binding IDA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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