1139


Homo sapiens (NCBI)

Features
Gene ID: 1139
  
Biological name :
  
Synonyms : cholinergic receptor nicotinic alpha 7 subunit / CHRNA7 / CHRNA7-2|NACHRA7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210123_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016877373.1
RefSeq - 1034589592
RefSeq - 1034589594
RefSeq - 1034589598
RefSeq - 299116991
RefSeq - 4502831
RefSeq - 767983174
RefSeq - 767983176
RefSeq - NC_000015.10
RefSeq - NG_009216.1
RefSeq - NT_187660.1
RefSeq - NW_011332701.1
RefSeq - NW_012132920.1
RefSeq - XP_011519478.2
RefSeq - XP_011519479.1
RefSeq - XP_011519480.1
RefSeq - XP_016877371.1
RefSeq - XP_016877372.1
RefSeq - 1034589590
RefSeq - NP_000737.1
RefSeq - NP_001177384.1
RefSeq - NM_000746.5
RefSeq - NM_001190455.2
RefSeq - XM_011521177.2
RefSeq - XM_011521178.3
RefSeq - NR_046324.1
RefSeq - XM_017021882.1
RefSeq - XM_017021883.2
RefSeq - XM_017021884.1
RefSeq - XM_011521176.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000175344 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IDA
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation ISS
 biological_processGO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure IEA
 biological_processGO:0006811 ion transport NAS
 biological_processGO:0006816 calcium ion transport IMP
 biological_processGO:0006874 cellular calcium ion homeostasis IMP
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007271 synaptic transmission, cholinergic IEA
 biological_processGO:0007611 learning or memory ISS
 biological_processGO:0007613 memory NAS
 biological_processGO:0007614 short-term memory ISS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0014061 regulation of norepinephrine secretion IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0032094 response to food IEA
 biological_processGO:0032225 regulation of synaptic transmission, dopaminergic IEA
 biological_processGO:0032691 negative regulation of interleukin-1 beta production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IMP
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034220 ion transmembrane transport IDA
 biological_processGO:0035094 response to nicotine ISS
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0048149 behavioral response to ethanol IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050808 synapse organization ISS
 biological_processGO:0050877 nervous system process IBA
 biological_processGO:0050890 cognition NAS
 biological_processGO:0050893 sensory processing ISS
 biological_processGO:0051247 positive regulation of protein metabolic process ISS
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060112 generation of ovulation cycle rhythm IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0095500 acetylcholine receptor signaling pathway ISS
 biological_processGO:0097061 dendritic spine organization ISS
 biological_processGO:0098815 modulation of excitatory postsynaptic potential ISS
 biological_processGO:0140059 dendrite arborization ISS
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation ISS
 biological_processGO:1901214 regulation of neuron death ISS
 biological_processGO:1902004 positive regulation of amyloid-beta formation ISS
 biological_processGO:1902430 negative regulation of amyloid-beta formation IGI
 biological_processGO:1902991 regulation of amyloid precursor protein catabolic process IGI
 biological_processGO:1904645 response to amyloid-beta ISS
 biological_processGO:1905144 response to acetylcholine ISS
 biological_processGO:1905906 regulation of amyloid fibril formation ISS
 biological_processGO:1905920 positive regulation of CoA-transferase activity ISS
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0044853 plasma membrane raft ISS
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0098794 postsynapse TAS
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0005216 ion channel activity IDA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IBA
 molecular_functionGO:0005262 calcium channel activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015276 ligand-gated ion channel activity TAS
 molecular_functionGO:0015464 acetylcholine receptor activity IDA
 molecular_functionGO:0015643 toxic substance binding IDA
 molecular_functionGO:0017081 chloride channel regulator activity IDA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity ISS
 molecular_functionGO:0042166 acetylcholine binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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