1147


Homo sapiens (NCBI)

Features
Gene ID: 1147
  
Biological name :
  
Synonyms : CHUK / conserved helix-loop-helix ubiquitous kinase / IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209666_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1004170674
RefSeq - 1034566254
RefSeq - 1034566257
RefSeq - 1034566259
RefSeq - 62241001
RefSeq - NC_000010.11
RefSeq - NG_028023.1
RefSeq - NP_001269.3
RefSeq - NP_001307857.1
RefSeq - XP_016871100.1
RefSeq - XP_016871101.1
RefSeq - XP_016871102.1
RefSeq - XM_017015612.1
RefSeq - XM_017015613.1
RefSeq - NM_001278.4
RefSeq - NM_001320928.1
RefSeq - XR_001747011.1
RefSeq - XR_001747010.1
RefSeq - XM_017015611.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000213341 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007252 I-kappaB phosphorylation TAS
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0010034 response to acetate IEA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033194 response to hydroperoxide IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IBA
 biological_processGO:0034614 cellular response to reactive oxygen species IMP
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0038061 NIK/NF-kappaB signaling TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0051146 striated muscle cell differentiation IEA
 biological_processGO:0051403 stress-activated MAPK cascade TAS
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0071276 cellular response to cadmium ion IMP
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0098586 cellular response to virus IMP
 biological_processGO:1902741 positive regulation of interferon-alpha secretion IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008385 IkappaB kinase complex TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008384 IkappaB kinase activity TAS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0097110 scaffold protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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