11792


Mus musculus (NCBI)

Features
Gene ID: 11792
  
Biological name :
  
Synonyms : APE|Apex|HAP1|Ref-1 / Apex1 / apurinic/apyrimidinic endonuclease 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416135_at (Mouse Genome 430 2.0 Array)   1437715_x_at (Mouse Genome 430 2.0 Array)   1456079_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6753086
RefSeq - NC_000080.6
RefSeq - NP_033817.1
RefSeq - NM_009687.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000035960 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance ISO
 biological_processGO:0006281 DNA repair ISO
 biological_processGO:0006284 base-excision repair ISO
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007568 aging ISO
 biological_processGO:0014912 negative regulation of smooth muscle cell migration ISO
 biological_processGO:0042981 regulation of apoptotic process ISO
 biological_processGO:0043488 regulation of mRNA stability ISO
 biological_processGO:0045454 cell redox homeostasis IDA
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0080111 DNA demethylation ISO
 biological_processGO:0097698 telomere maintenance via base-excision repair ISO
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005667 transcription factor complex ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003684 damaged DNA binding ISO
 molecular_functionGO:0003691 double-stranded telomeric DNA binding ISO
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity ISO
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004521 endoribonuclease activity ISO
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004528 phosphodiesterase I activity IBA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity ISO
 molecular_functionGO:0008309 double-stranded DNA exodeoxyribonuclease activity ISO
 molecular_functionGO:0008311 double-stranded DNA 3"-5" exodeoxyribonuclease activity IBA
 molecular_functionGO:0008408 3"-5" exonuclease activity ISO
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base ISO
 molecular_functionGO:0031490 chromatin DNA binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046872 metal ion binding ISO
 molecular_functionGO:0051059 NF-kappaB binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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