12154


Mus musculus (NCBI)
regulationcellcardiacmuscledevelopmenthearthypertrophysmadproteingrowthreceptormorphogenesisproliferationactivitybindingmigrationpathway-restrictedphosphorylationsignalingpathwaysarcomereorganizationtissueventricularextracellularfactoradhesionmulticellularorganismadult

Features
Gene ID: 12154
  
Biological name :
  
Synonyms : b2b2711Clo / Bmp10 / bone morphogenetic protein 10
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421763_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 157837977
RefSeq - NC_000072.6
RefSeq - NP_033886.2
RefSeq - NM_009756.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000030046 to get all the annotations available for this gene.


Gene Ontology (GO)
cell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell adhesionanatomical structure developmentlocalization of cellmovement of cell or subcellular componenttissue migrationsystem processorganic substance metabolic processnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processcellular response to stimuluscellular component organizationcell growthbiosynthetic processresponse to endogenous stimulusresponse to chemicalcell deathcellular component biogenesiscellular developmental processactin filament-based processmuscle cell proliferationdevelopmental growthresponse to stresscell cell adhesionanatoanatomical structure developmentlocallocalization of cellmovemmovement of cell or subcellular componenttissutissue migrationsystesystem processorganorganic substance metabolic processnitronitrogen compound metabolic processcell cell communicationcellucellular metabolic processprimaprimary metabolic processcellucellular response to stimuluscellucellular component organizationcell cell growthbiosybiosynthetic processresporesponse to endogenous stimulusresporesponse to chemicalcell cell deathcellucellular component biogenesiscellucellular developmental processactinactin filament-based processmusclmuscle cell proliferationdeveldevelopmental growthresporesponse to stress
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regioncellorganellesupramolecular complexextracellular regionextracellular regioncellcellorganelleorganellesupramolecular complexsupramolecular complex
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007512 adult heart development IMP
 biological_processGO:0010596 negative regulation of endothelial cell migration ISO
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISO
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030336 negative regulation of cell migration ISO
 biological_processGO:0030509 BMP signaling pathway ISO
 biological_processGO:0032924 activin receptor signaling pathway ISO
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0045214 sarcomere organization ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0048468 cell development IBA
 biological_processGO:0055009 atrial cardiac muscle tissue morphogenesis IEP
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IMP
 biological_processGO:0055015 ventricular cardiac muscle cell development IDA
 biological_processGO:0055117 regulation of cardiac muscle contraction ISO
 biological_processGO:0060038 cardiac muscle cell proliferation IMP
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation IMP
 biological_processGO:0060298 positive regulation of sarcomere organization ISO
 biological_processGO:0060347 heart trabecula formation IMP
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0060395 SMAD protein signal transduction IBA
 biological_processGO:0061036 positive regulation of cartilage development IDA
 biological_processGO:1903242 regulation of cardiac muscle hypertrophy in response to stress ISO
 biological_processGO:2000138 positive regulation of cell proliferation involved in heart morphogenesis IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0030018 Z disc ISO
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0005179 hormone activity ISO
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0031433 telethonin binding ISO
 molecular_functionGO:0033612 receptor serine/threonine kinase binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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