12631


Mus musculus (NCBI)

Features
Gene ID: 12631
  
Biological name :
  
Synonyms : AA959946|Cof / Cfl1 / cofilin 1, non-muscle
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1448346_at (Mouse Genome 430 2.0 Array)   1455138_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6680924
RefSeq - NC_000085.6
RefSeq - NP_031713.1
RefSeq - NM_007687.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000056201 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0001842 neural fold formation IMP
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006606 protein import into nucleus ISO
 biological_processGO:0007010 cytoskeleton organization ISO
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007162 negative regulation of cell adhesion ISO
 biological_processGO:0010592 positive regulation of lamellipodium assembly ISO
 biological_processGO:0010593 negative regulation of lamellipodium assembly ISO
 biological_processGO:0022604 regulation of cell morphogenesis ISO
 biological_processGO:0030010 establishment of cell polarity IMP
 biological_processGO:0030030 cell projection organization ISO
 biological_processGO:0030042 actin filament depolymerization ISO
 biological_processGO:0030043 actin filament fragmentation IDA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030835 negative regulation of actin filament depolymerization ISO
 biological_processGO:0030836 positive regulation of actin filament depolymerization IMP
 biological_processGO:0031915 positive regulation of synaptic plasticity ISO
 biological_processGO:0032232 negative regulation of actin filament bundle assembly ISO
 biological_processGO:0043200 response to amino acid IDA
 biological_processGO:0044794 positive regulation by host of viral process ISO
 biological_processGO:0045792 negative regulation of cell size ISO
 biological_processGO:0045862 positive regulation of proteolysis ISO
 biological_processGO:0051511 negative regulation of unidimensional cell growth ISO
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0060999 positive regulation of dendritic spine development ISO
 biological_processGO:0061001 regulation of dendritic spine morphogenesis ISO
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0071347 cellular response to interleukin-1 ISO
 biological_processGO:0071354 cellular response to interleukin-6 ISO
 biological_processGO:0071356 cellular response to tumor necrosis factor ISO
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus ISO
 biological_processGO:1902951 negative regulation of dendritic spine maintenance ISO
 biological_processGO:1904783 positive regulation of NMDA glutamate receptor activity ISO
 biological_processGO:1905873 positive regulation of protein localization to cell leading edge ISO
 biological_processGO:1905875 negative regulation of postsynaptic density organization ISO
 biological_processGO:1990314 cellular response to insulin-like growth factor stimulus ISO
 biological_processGO:2000146 negative regulation of cell motility ISO
 biological_processGO:2000147 positive regulation of cell motility ISO
 biological_processGO:2000784 positive regulation of establishment of cell polarity regulating cell shape ISO
 biological_processGO:2000814 positive regulation of barbed-end actin filament capping ISO
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium ISO
 cellular_componentGO:0030175 filopodium ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0031252 cell leading edge ISO
 cellular_componentGO:0031966 mitochondrial membrane ISO
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043197 dendritic spine ISO
 cellular_componentGO:0090732 cofilin-actin rod ISO
 cellular_componentGO:0097060 synaptic membrane ISO
 molecular_functionGO:0003779 actin binding ISO
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0051015 actin filament binding ISO
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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